在巴基斯坦类风湿关节炎队列（FAF-RA）研究中通过FACIT-F量表进行疲劳评估。
Fatigue assessment by FACIT-F scale in Pakistani cohort with Rheumatoid Arthritis (FAF-RA) study.
作者信息
Wagan Abrar Ahmed, Raheem Abdul, Bhatti Afra, Zafar Taimoor
机构信息
Dr. Abrar Ahmed Wagan, MBBS, FCPS (Medicine), FCPS (Rheumatology), FACR. Assistant Professor, Indus Medical College, Tando Mohammad Khan, Pakistan.
Dr. Abdul Raheem, MBBS. Postgraduate Trainee, Central Park Medical College Lahore, Lahore, Pakistan.
出版信息
Pak J Med Sci. 2021 Jul-Aug;37(4):1025-1030. doi: 10.12669/pjms.37.4.3602.
OBJECTIVE
To fine out fatigue frequency and severity by FACIT-F scale in Pakistani cohort with rheumatoid arthritis.
METHODS
This study was conducted at department of Medicine division of rheumatology CPMC Lahore. After the approval of IRB, 192 patients of RA were recruited. Written, informed consent was taken, demographic details were noted, patients filled the URDU version of FACIT-F (fatigue severity scale). 5-ml of blood was taken for fasting blood sugar, viral markers and ESR by a trained phlebotomist. Each individual's disease activity was assessed by DAS-28 and FACIT-F score was calculated.
RESULTS
The Mean age (39.9±10.5) years, (71.9%) were females. Fatigue frequency was 62% (n=126), age, education, hypertension, DAS-28, exercise levels and HCV gives significant association with fatigue score. Linear regression analysis, results showed one unit increase in DAS-28 will gives 2.71 unit increases in fatigue scores(P <0.05).
CONCLUSIONS
We have very high frequency of fatigue in RA, increases with disease activity & associated conditions.
目的
通过FACIT - F量表找出巴基斯坦类风湿关节炎队列中的疲劳频率和严重程度。
方法
本研究在拉合尔CPMC风湿病学部内科进行。经机构审查委员会批准后，招募了192例类风湿关节炎患者。获取书面知情同意书，记录人口统计学细节，患者填写乌尔都语版的FACIT - F（疲劳严重程度量表）。由训练有素的采血员采集5毫升血液用于检测空腹血糖、病毒标志物和红细胞沉降率。通过DAS - 28评估每个个体的疾病活动度并计算FACIT - F评分。
结果
平均年龄（39.9±10.5）岁，女性占（71.9%）。疲劳频率为62%（n = 126），年龄、教育程度、高血压、DAS - 28、运动水平和丙型肝炎病毒与疲劳评分有显著关联。线性回归分析结果显示，DAS - 28每增加一个单位，疲劳评分将增加2.71个单位（P < 0.05）。
结论
我们发现类风湿关节炎患者中疲劳的发生率很高，且随着疾病活动度及相关状况增加。
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