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低度恶性潜能的乳腺浸润性癌。

Breast carcinomas of low malignant potential.

机构信息

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School; Breast Oncology Program, Dana-Farber/Brigham and Women's Cancer Center, 75 Francis Street, Boston, MA, 02115, USA.

Department of Pathology and Neuropathology, Tübingen University Hospital and Comprehensive Cancer Center Tübingen-Stuttgart, Tübingen, Germany.

出版信息

Virchows Arch. 2022 Jan;480(1):5-19. doi: 10.1007/s00428-021-03163-w. Epub 2021 Jul 22.

DOI:10.1007/s00428-021-03163-w
PMID:34292391
Abstract

Some breast carcinomas have a very low likelihood of metastasis to regional lymph nodes and distant sites and may be considered carcinomas of low malignant potential. In this article, we review the clinical, pathologic, immunophenotypic, and molecular features of selected breast carcinomas of low malignant potential including low-grade adenosquamous carcinoma, fibromatosis-like metaplastic carcinoma, encapsulated papillary carcinoma, solid papillary carcinoma, and tall cell carcinoma with reversed polarity.

摘要

一些乳腺癌转移到区域淋巴结和远处部位的可能性非常低,因此可能被认为是恶性潜能较低的癌。本文回顾了几种低恶性潜能乳腺癌的临床、病理、免疫表型和分子特征,包括低级别腺鳞癌、纤维瘤样化生癌、包裹性乳头状癌、实性乳头状癌和具有极性反转的高细胞癌。

相似文献

1
Breast carcinomas of low malignant potential.低度恶性潜能的乳腺浸润性癌。
Virchows Arch. 2022 Jan;480(1):5-19. doi: 10.1007/s00428-021-03163-w. Epub 2021 Jul 22.
2
Fibromatosislike metaplastic carcinoma of the breast as a diagnostic pitfall for fine needle aspiration cytology: a case report.乳腺纤维瘤样化生癌作为细针穿刺细胞学检查的诊断陷阱:一例报告
Acta Cytol. 2010 Sep-Oct;54(5):712-6. doi: 10.1159/000325238.
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Low-grade fibromatosis-like spindle cell carcinoma of the breast.乳腺低度纤维瘤样梭形细胞癌
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4
Solid papillary carcinoma with reverse polarity of the breast harbors specific morphologic, immunohistochemical and molecular profile in comparison with other benign or malignant papillary lesions of the breast: a comparative study of 9 additional cases.实性乳头状癌伴乳腺极性反转与其他乳腺良恶性乳头状病变相比具有特定的形态学、免疫组织化学和分子特征:9 例附加病例的对比研究。
Mod Pathol. 2018 Sep;31(9):1367-1380. doi: 10.1038/s41379-018-0047-1. Epub 2018 May 21.
5
Immunohistochemical analysis of IDH2 R172 hotspot mutations in breast papillary neoplasms: applications in the diagnosis of tall cell carcinoma with reverse polarity.免疫组织化学分析乳腺乳头状肿瘤中 IDH2 R172 热点突变:在诊断具有反向极性的高细胞癌中的应用。
Mod Pathol. 2020 Jun;33(6):1056-1064. doi: 10.1038/s41379-019-0442-2. Epub 2020 Jan 2.
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Solid papillary carcinoma of the breast: A special entity needs to be distinguished from conventional invasive carcinoma avoiding over-treatment.乳腺实性乳头状癌:一种特殊类型,需与传统浸润性癌相鉴别以避免过度治疗。
Breast. 2016 Apr;26:67-72. doi: 10.1016/j.breast.2015.12.015. Epub 2016 Jan 29.
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Low-grade (fibromatosis-like) spindle cell carcinoma of the breast.乳腺低级别(纤维瘤病样)梭形细胞癌
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本文引用的文献

1
A difficult-to-diagnose fibromatosis-like metaplastic carcinoma of the breast: a case report.一例难以诊断的乳腺纤维瘤样化生癌:病例报告
Surg Case Rep. 2021 Jan 12;7(1):16. doi: 10.1186/s40792-021-01110-0.
2
Tall cell carcinoma of the breast with reversed polarity (TCCRP) with mutations in the IDH2 and PIK3CA genes: a case report.伴有IDH2和PIK3CA基因突变的极性反转性乳腺高细胞癌(TCCRP):一例报告
Mol Biol Rep. 2020 Jun;47(6):4917-4921. doi: 10.1007/s11033-020-05553-w. Epub 2020 May 30.
3
Fibromatosis-like metaplastic carcinoma: a case report and review of the literature.
靶向低风险三阴性乳腺癌:新时代降阶梯治疗策略综述
Transl Breast Cancer Res. 2024 Nov 27;6:4. doi: 10.21037/tbcr-24-28. eCollection 2025.
4
Low-Grade Adenosquamous Carcinoma of the Breast: A Single-Center Retrospective Study and a Systematic Literature Review.乳腺低级别腺鳞癌:一项单中心回顾性研究及系统文献综述
Cancers (Basel). 2024 Dec 20;16(24):4246. doi: 10.3390/cancers16244246.
5
A new subtype of papillary ductal carcinoma in situ with tall cell and reversed polarity morphology: a rare case report.一种具有高细胞和极性反转形态的原位乳头状导管癌新亚型:一例罕见病例报告。
BMC Womens Health. 2024 Dec 19;24(1):640. doi: 10.1186/s12905-024-03489-y.
6
Hormone receptor expression in low-grade adenosquamous carcinoma of the breast progressing to high-grade metaplastic carcinoma: A case report.乳腺低级别腺样鳞状细胞癌进展为高级别化生性癌中激素受体的表达:一例报告。
Medicine (Baltimore). 2024 Jul 26;103(30):e39131. doi: 10.1097/MD.0000000000039131.
7
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools.乳腺疾病的分子病理学:诊断、预后和治疗工具。
Virchows Arch. 2024 Feb;484(2):247-261. doi: 10.1007/s00428-023-03709-0. Epub 2023 Nov 28.
纤维瘤病样化生性癌:一例报告并文献复习。
Diagn Pathol. 2020 Mar 3;15(1):20. doi: 10.1186/s13000-020-00943-x.
4
Fibromatosis-like metaplastic carcinoma of breast: a challenge for clinicopathologic diagnosis.乳腺纤维瘤样化生性癌:临床病理诊断的一项挑战
Int J Clin Exp Pathol. 2018 Jul 1;11(7):3691-3696. eCollection 2018.
5
Immunohistochemical analysis of IDH2 R172 hotspot mutations in breast papillary neoplasms: applications in the diagnosis of tall cell carcinoma with reverse polarity.免疫组织化学分析乳腺乳头状肿瘤中 IDH2 R172 热点突变:在诊断具有反向极性的高细胞癌中的应用。
Mod Pathol. 2020 Jun;33(6):1056-1064. doi: 10.1038/s41379-019-0442-2. Epub 2020 Jan 2.
6
Papillary Lesions of the Male Breast: A Study of 117 Cases and Brief Review of the Literature Demonstrate a Broad Clinicopathologic Spectrum.男性乳腺的乳头状病变:117 例研究及文献复习显示出广泛的临床病理谱。
Am J Surg Pathol. 2020 Jan;44(1):68-76. doi: 10.1097/PAS.0000000000001340.
7
Breast Tumor Resembling the Tall Cell Variant of Papillary Thyroid Carcinoma: Molecular Characterization by Next-Generation Sequencing and Histopathological Comparison With Tall Cell Papillary Carcinoma of Thyroid.类似甲状腺乳头状癌高细胞变体的乳腺肿瘤:通过二代测序进行分子特征分析及与甲状腺高细胞乳头状癌的组织病理学比较
Int J Surg Pathol. 2019 Apr;27(2):134-141. doi: 10.1177/1066896918800779. Epub 2018 Sep 18.
8
Solid papillary carcinoma with reverse polarity of the breast harbors specific morphologic, immunohistochemical and molecular profile in comparison with other benign or malignant papillary lesions of the breast: a comparative study of 9 additional cases.实性乳头状癌伴乳腺极性反转与其他乳腺良恶性乳头状病变相比具有特定的形态学、免疫组织化学和分子特征:9 例附加病例的对比研究。
Mod Pathol. 2018 Sep;31(9):1367-1380. doi: 10.1038/s41379-018-0047-1. Epub 2018 May 21.
9
Solid papillary breast carcinomas resembling the tall cell variant of papillary thyroid neoplasms (solid papillary carcinomas with reverse polarity) harbour recurrent mutations affecting IDH2 and PIK3CA: a validation cohort.酷似甲状腺乳头状肿瘤 tall cell 型的实性乳头状乳腺癌(具有反向极性的实性乳头状癌)中存在 IDH2 和 PIK3CA 频发突变:验证队列研究。
Histopathology. 2018 Aug;73(2):339-344. doi: 10.1111/his.13522. Epub 2018 Jun 1.
10
Solid Papillary Breast Carcinomas Resembling the Tall Cell Variant of Papillary Thyroid Neoplasms: A Unique Invasive Tumor With Indolent Behavior.类似甲状腺乳头状肿瘤高细胞变体的乳腺实性乳头状癌:一种具有惰性生物学行为的独特浸润性肿瘤
Am J Surg Pathol. 2017 Jul;41(7):887-895. doi: 10.1097/PAS.0000000000000853.