Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan.
Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
BMJ Case Rep. 2021 Jul 22;14(7):e240342. doi: 10.1136/bcr-2020-240342.
Insulin oedema is a rare complication of insulin treatment characterised by an absence of heart, liver and renal involvement. Insulin oedema typically develops in the lower extremities or, less frequently, as generalised oedema after initiation of insulin therapy. We report a 59-year-old man with poorly controlled type 2 diabetes who developed oedema in his penis and scrotum accompanied by weight gain following intensive insulin therapy. His oedema improved after reduction of the daily insulin injection dose and treatment for urinary retention. Penile and scrotal oedema is a rare physical finding for the patient with diabetes. Therefore, in patients with poorly controlled diabetes who have started insulin therapy, physicians should pay attention to urinary retention and do not miss changes in weight gain or oedema in the lower body, including the perineal region.
胰岛素水肿是胰岛素治疗的一种罕见并发症,其特征为无心脏、肝脏和肾脏受累。胰岛素水肿通常在开始胰岛素治疗后出现在下肢,或较少见地出现全身性水肿。我们报告了一例 59 岁的男性,患有未控制的 2 型糖尿病,在强化胰岛素治疗后出现阴茎和阴囊水肿,并伴有体重增加。他的水肿在减少每日胰岛素注射剂量和治疗尿潴留后得到改善。阴茎和阴囊水肿是糖尿病患者罕见的体格检查发现。因此,对于开始胰岛素治疗且血糖控制不佳的患者,医生应注意尿潴留,不要错过体重增加或下肢(包括会阴区域)水肿的变化。