1,2-苯并异恶唑对硝基炔环异构化反应中α-氧代金卡宾的分子间拦截：官能化喹唑啉1-氧化物的合成
Intermolecular Interception of α-Oxo Gold Carbenes of Nitroalkyne Cycloisomerization with 1,2-Benzo[]isoxazole: Synthesis of Functionalized Quinazoline 1-Oxides.
作者信息
Dhote Pawan S, Pund Kishor A, Ramana Chepuri V
机构信息
Division of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
出版信息
J Org Chem. 2021 Aug 6;86(15):10874-10882. doi: 10.1021/acs.joc.1c01221. Epub 2021 Jul 27.
The known nitrogen-transfer reagent 1,2-benzo[]isoxazole has been used to trap the postulated α-oxo gold carbene intermediate involved in the [Au]-catalyzed internal redox process of 2-alkynylnitrobenzenes. This process led us to develop a general convergent method for the synthesis of highly functionalized quinazoline 1-oxides.
已知的氮转移试剂1,2-苯并异恶唑已被用于捕获假定的α-氧代金卡宾中间体，该中间体参与了[金]催化的2-炔基硝基苯的内部氧化还原过程。这一过程促使我们开发出一种通用的收敛方法，用于合成高度官能化的喹唑啉1-氧化物。
Zotero 插件