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舒张期负荷试验与H2FPEF评分之间的关联

[Association between diastolic stress test and H2FPEF score].

作者信息

Rendón-Giraldo Jairo A, Lema Camila, Saldarriaga-Giraldo Clara I

机构信息

Department of Cardiology, CES University; Fellow of the American College of Cardiology (FACC) and the European Society of Cardiology (FESC), Universidad de Antioquia, Medellín, Colombia.

Department of Cardiology, CES University, Universidad de Antioquia, Medellín, Colombia.

出版信息

Arch Cardiol Mex. 2022 Apr 4;92(2):203-208. doi: 10.24875/ACM.21000053.

DOI:10.24875/ACM.21000053
PMID:34320623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9005186/
Abstract

OBJECTIVE

Heart failure with preserved ejection fraction is a highly prevalent disease; some advances for improving the diagnosis are the development of the H2FPEF score and the diastolic stress test for the evaluation of diastolic function. The objective is to describe the clinical and echocardiographic characteristics of patients referred for stress tests, and the association between the H2FPEF score and the results of the diastolic test.

METHODS

This is an analytical, observational, retrospective study. An exercise stress test was performed. The Chi-square test was used to establish an association between H2FpEF score and diastolic stress test results. Patients over the age of 18, in sinus rhythm, with the left ventricular ejection fraction > 54%, with no more than mild diastolic dysfunction on the baseline echocardiogram were included in the study.

RESULTS

A total of 99 patients met the eligibility criteria. About 49.5% were women, median age was 62.2 years. The H2FPEF score was low in 27.2%, intermediate 71.7%, and 1% in the high range. There was a high prevalence of hypertension 58.6%, diabetes 12.1%, and coronary disease 20.2%. The stress test was positive for diastolic dysfunction in 36.4% of the patients. A statistically significant association was found between the H2FPEF score and the diastolic stress test (p = 0.02).

CONCLUSIONS

Although clinical scores such as H2FPEF help identify patients, a high percentage of patients are classified in the intermediate range. The diastolic stress test can help to make the diagnosis of diastolic function in this group of patients.

摘要

目的

射血分数保留的心力衰竭是一种高度流行的疾病;改善诊断的一些进展包括H2FPEF评分的发展以及用于评估舒张功能的舒张期负荷试验。目的是描述接受负荷试验患者的临床和超声心动图特征,以及H2FPEF评分与舒张期试验结果之间的关联。

方法

这是一项分析性、观察性、回顾性研究。进行了运动负荷试验。采用卡方检验来确定H2FpEF评分与舒张期负荷试验结果之间的关联。研究纳入了年龄超过18岁、窦性心律、左心室射血分数>54%、基线超声心动图上舒张功能障碍不超过轻度的患者。

结果

共有99名患者符合入选标准。约49.5%为女性,中位年龄为62.2岁。H2FPEF评分低的占27.2%,中等的占71.7%,高的占1%。高血压患病率为58.6%,糖尿病为12.1%,冠心病为20.2%。36.4%的患者负荷试验舒张功能障碍呈阳性。发现H2FPEF评分与舒张期负荷试验之间存在统计学显著关联(p = 0.02)。

结论

尽管诸如H2FPEF等临床评分有助于识别患者,但仍有很高比例的患者被归类为中等范围。舒张期负荷试验有助于对这组患者的舒张功能进行诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/9005186/132c0ecfee09/6936AX212-ACM-92-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/9005186/132c0ecfee09/6936AX212-ACM-92-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/9005186/132c0ecfee09/6936AX212-ACM-92-203-g001.jpg

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