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横断面部分相关网络的探索价值:预测边缘型人格障碍变化轨迹之间的关系。

The exploratory value of cross-sectional partial correlation networks: Predicting relationships between change trajectories in borderline personality disorder.

机构信息

Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Department of Psychological Methods, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

PLoS One. 2021 Jul 30;16(7):e0254496. doi: 10.1371/journal.pone.0254496. eCollection 2021.

DOI:10.1371/journal.pone.0254496
PMID:34329316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8323921/
Abstract

OBJECTIVE

Within the network approach to psychopathology, cross-sectional partial correlation networks have frequently been used to estimate relationships between symptoms. The resulting relationships have been used to generate hypotheses about causal links between symptoms. In order to justify such exploratory use of partial correlation networks, one needs to assume that the between-subjects relationships in the network approximate systematic within-subjects relationships, which are in turn the results of some within-subjects causal mechanism. If this assumption holds, relationships in the network should be mirrored by relationships between symptom changes; if links in networks approximate systematic within-subject relationships, change in a symptom should relate to change in connected symptoms.

METHOD

To investigate this implication, we combined longitudinal data on the Borderline Personality Disorder Severity Index from four samples of borderline personality disorder patients (N = 683). We related parameters from baseline partial correlation networks of symptoms to relationships between change trajectories of these symptoms.

RESULTS

Across multiple levels of analysis, our results showed that parameters from baseline partial correlation networks are strongly predictive of relationships between change trajectories.

CONCLUSIONS

By confirming its implication, our results support the idea that cross-sectional partial correlation networks hold a relevant amount of information about systematic within-subjects relationships and thereby have exploratory value to generate hypotheses about the causal dynamics between symptoms.

摘要

目的

在精神病理学的网络方法中,横截面部分相关网络经常被用来估计症状之间的关系。由此产生的关系被用来生成关于症状之间因果关系的假设。为了证明这种对部分相关网络的探索性使用是合理的,需要假设网络中的个体间关系近似于系统的个体内关系,而个体内关系又是某种个体内因果机制的结果。如果这一假设成立,网络中的关系应该与症状变化之间的关系相呼应;如果网络中的联系近似于系统的个体内关系,那么一个症状的变化应该与相关症状的变化有关。

方法

为了研究这一含义,我们结合了来自四个边缘型人格障碍患者样本(N=683)的边缘型人格障碍严重程度指数的纵向数据。我们将症状的基线部分相关网络的参数与这些症状的变化轨迹之间的关系联系起来。

结果

在多个分析层次上,我们的结果表明,基线部分相关网络的参数与这些症状的变化轨迹之间的关系具有很强的预测性。

结论

通过证实这一含义,我们的结果支持了这样一种观点,即横截面部分相关网络包含了关于系统个体内关系的大量信息,因此具有探索性价值,可以生成关于症状之间因果动态的假设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/642f/8323921/29287255d778/pone.0254496.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/642f/8323921/29287255d778/pone.0254496.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/642f/8323921/29287255d778/pone.0254496.g001.jpg

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