Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy; Microbiome Research Hub, University of Parma, Parma, Italy.
Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy; Microbiome Research Hub, University of Parma, Parma, Italy.
Curr Opin Biotechnol. 2022 Feb;73:81-87. doi: 10.1016/j.copbio.2021.07.012. Epub 2021 Jul 30.
Current scientific literature has identified the infant gut microbiota as a multifaceted organ influencing a range of aspects of host-health and development. Many scientific studies have focused on characterizing the main microbial taxa that constitute the resident bacterial population of the infant gut. This has generated a wealth of information on the bacterial composition of the infant gut microbiota, and on the functional role/s exerted by their key microbial members. In this context, one of the most prevalent, abundant and investigated microbial taxon in the human infant gut is the genus Bifidobacterium, due to the purported beneficial activities is bestows upon its host. This review discusses the most recent findings regarding the infant gut microbiota with a particular focus on the molecular mechanisms by which bifidobacteria impact on host health and well-being.
目前的科学文献已经确定婴儿肠道微生物群是一个多方面的器官，影响宿主健康和发育的多个方面。许多科学研究都集中在描述构成婴儿肠道常驻细菌种群的主要微生物类群。这为婴儿肠道微生物群的细菌组成以及其关键微生物成员发挥的功能作用提供了丰富的信息。在这方面，由于双歧杆菌对宿主有益的活动，在人类婴儿肠道中最普遍、最丰富和研究最多的微生物类群之一就是双歧杆菌属。本文讨论了关于婴儿肠道微生物群的最新发现，特别关注双歧杆菌影响宿主健康和福祉的分子机制。
