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经皮内镜腰椎间盘切除术与开放腰椎间盘切除术术后再手术和感染的风险:一项基于全国人群的研究。

Risk of reoperation and infection after percutaneous endoscopic lumbar discectomy and open lumbar discectomy : a nationwide population-based study.

机构信息

Department of Orthopaedics, Korea University College of Medicine, Anam Hospital, Seoul, South Korea.

Department of Biostatistics, Korea University College of Medicine, Seoul, South Korea.

出版信息

Bone Joint J. 2021 Aug;103-B(8):1392-1399. doi: 10.1302/0301-620X.103B8.BJJ-2020-2541.R2.

Abstract

AIMS

Open discectomy (OD) is the standard operation for lumbar disc herniation (LDH). Percutaneous endoscopic lumbar discectomy (PELD), however, has shown similar outcomes to OD and there is increasing interest in this procedure. However despite improved surgical techniques and instrumentation, reoperation and infection rates continue and are reported to be between 6% and 24% and 0.7% and 16%, respectively. The objective of this study was to compare the rate of reoperation and infection within six months of patients being treated for LDH either by OD or PELD.

METHODS

In this retrospective, nationwide cohort study, the Korean National Health Insurance database from 1 January 2007 to 31 December 2018 was reviewed. Data were extracted for patients who underwent OD or PELD for LDH without a history of having undergone either procedure during the preceding year. Individual patients were followed for six months through their encrypted unique resident registration number. The primary endpoints were rates of reoperation and infection during the follow-up period. Other risk factors for reoperation and infection were also evalulated.

RESULTS

Out of 549,531 patients, 522,640 had undergone OD (95.11%) and 26,891 patients had undergone PELD (4.89%). Reoperation rates within six months were 2.28% in the OD group, and 5.38% in the PELD group. Infection rates were 1.18% in OD group and 0.83% in PELD group. The risk of reoperation was lower for patients with OD than for patients with PELD (adjusted hazard ratio (HR) 0.38). The risk of infection was higher for patients with OD than for patients undergoing PELD (HR, 1.325).

CONCLUSION

Compared with the OD group, the PELD group showed higher reoperation rates and lower infection rates. Cite this article:  2021;103-B(8):1392-1399.

摘要

目的

开放式椎间盘切除术(OD)是治疗腰椎间盘突出症(LDH)的标准手术。然而,经皮内镜腰椎间盘切除术(PELD)的结果与 OD 相似,因此人们对该手术越来越感兴趣。尽管手术技术和器械有所改进,但再次手术和感染的发生率仍然存在,分别为 6%至 24%和 0.7%至 16%。本研究的目的是比较接受 OD 或 PELD 治疗的 LDH 患者在术后 6 个月内再次手术和感染的发生率。

方法

在这项回顾性的全国性队列研究中,我们对 2007 年 1 月 1 日至 2018 年 12 月 31 日期间的韩国国家健康保险数据库进行了回顾。纳入无既往一年内行 OD 或 PELD 治疗史的患者。通过他们加密的唯一居民登记号码,对每个患者进行了为期 6 个月的随访。主要终点是随访期间再次手术和感染的发生率。还评估了其他与再次手术和感染相关的风险因素。

结果

在 549531 名患者中,522640 名患者接受了 OD(95.11%),26891 名患者接受了 PELD(4.89%)。OD 组术后 6 个月内再次手术率为 2.28%,PELD 组为 5.38%。OD 组感染率为 1.18%,PELD 组为 0.83%。与 PELD 组相比,OD 组再次手术的风险较低(调整后的风险比(HR)0.38)。OD 组感染的风险高于 PELD 组(HR 1.325)。

结论

与 OD 组相比,PELD 组的再次手术率较高,感染率较低。

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