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单侧双门孔内镜减压治疗重度退行性腰椎管狭窄症:与开放式椎间盘切除术减压的比较研究

Decompression unilateral biportal endoscopy for severe degenerative lumbar spinal stenosis: A comparative study with decompression open discectomy.

作者信息

Tan Bing, Yang Qi-Yuan, Fan Bin, Xiong Chuang

机构信息

Department of Spine Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.

Department of Orthopedic, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Front Neurol. 2023 Feb 22;14:1132698. doi: 10.3389/fneur.2023.1132698. eCollection 2023.

Abstract

BACKGROUND

Previous studies have shown that the Unilateral Biportal Endoscopy is an effective and safety surgery for sufficient decompression of degenerative lumbar spinal stenosis. However, data are lacking in terms of its benefits when compared with conventional open lumbar discectomy (OLD), especially in patients with severe degenerative lumbar spinal stenosis (DLSS).

AIM

To compare the clini cal outcomes of two types decompressive surgery: unilateral biportal endoscopy-unilateral laminectomy bilateral decompression (UBE-ULBD) and conventional open lumbar discectomy (OLD) in severe degenerative lumbar spinal stenosis (DLSS).

METHODS

We retrospectively analyzed patients who underwent UBE-ULBD ( = 50, operated at 50 levels; UBE-ULBD group) and conventional open lumbar discectomy ( = 59, operated at 47 levels; OLD group) between February 2019 and July 2021. All patients were diagnosed with severe stenosis based on the Schizas classification (Grade C or D) on MRI. We compared radiographic and clinical outcome scores [including the visual analog scale (VAS), Oswestry Disability Index (ODI), and Zurich Claudication Questionnaire (ZCQ)] between the 2 groups at 1 year of follow-up. The radiographic evaluation included the cross-sectional area (CSA) of the thecal sac and paraspinal muscles on MRI. Fasting blood was drawn before and 1 and 7 days after the operation to detect creatine kinase (CK). Surgical data perioperative complications were also investigated.

RESULTS

The baseline demographic data of the 2 groups were comparable, including VAS, ODI and ZCQ scores, the cross-sectional area of the thecal sac and paraspinal muscles and creatine kinase levels. The dural sac CSA significantly increased post -operatively in both groups, which confirmed they benefited from comparable decompressive effects. The operative duration in the OLD group was less than the UBE-ULBD group (43.9 ± 5.6 min vs. 74.2 ± 9.3 min, < 0.05). The OLD group was associated with more estimated blood loss than the UBE-ULBD group (111.2 ± 25.0 ml vs. 41.5 ± 22.2 ml, < 0.05). The length of hospital stay (HS) was significantly longer in the OLD group than in the UBE-ULBD group (6.8 ± 1.6 vs. 4.0 ± 1.4 days, < 0.05). The VAS, ODI, and ZCQ scores improved in both groups after the operation. Serum creatine kinase values in the UBE-ULBD group were significantly lower than in the OLD group at 1 day after surgery (108. 1 ± 11.9 vs. 347.0 ± 19.5 U/L, < 0.05). The degree of paraspinal muscle atrophy in the UBE-ULBD group was significantly lower than in the OLD group at 1 year (4.50 ± 0.60 vs. 11.42 ± 0.87, < 0.05).

CONCLUSIONS

UBE-ULBD and conventional OLD demonstrate comparable short-term clinical outcomes in treating severe DLSS. However, UBE-ULBD surgery was associated with a shorter hospital stay, less EBL and paravertebral muscle injury than OLD surgery.

摘要

背景

既往研究表明,单侧双通道内镜手术是一种有效且安全的手术方式,可充分减压退变性腰椎管狭窄症。然而,与传统开放性腰椎间盘切除术(OLD)相比,其益处的数据尚缺乏,尤其是在重度退变性腰椎管狭窄症(DLSS)患者中。

目的

比较两种减压手术方式——单侧双通道内镜下单侧椎板切除双侧减压术(UBE - ULBD)和传统开放性腰椎间盘切除术(OLD)治疗重度退变性腰椎管狭窄症(DLSS)的临床疗效。

方法

回顾性分析2019年2月至2021年7月期间接受UBE - ULBD手术(n = 50,手术50个节段;UBE - ULBD组)和传统开放性腰椎间盘切除术(n = 59,手术47个节段;OLD组)的患者。所有患者均根据MRI上的Schizas分类(C级或D级)诊断为重度狭窄。我们比较了两组在随访1年时的影像学和临床结局评分[包括视觉模拟量表(VAS)、Oswestry功能障碍指数(ODI)和苏黎世跛行问卷(ZCQ)]。影像学评估包括MRI上硬脊膜囊和椎旁肌的横截面积(CSA)。在手术前、术后1天和7天抽取空腹血检测肌酸激酶(CK)。还调查了手术数据及围手术期并发症。

结果

两组的基线人口统计学数据具有可比性,包括VAS、ODI和ZCQ评分、硬脊膜囊和椎旁肌的横截面积以及肌酸激酶水平。两组术后硬脊膜囊CSA均显著增加,证实它们从相当的减压效果中获益。OLD组的手术时间短于UBE - ULBD组(43.9 ± 5.6分钟对74.2 ± 9.3分钟,P < 0.05)。OLD组的估计失血量多于UBE - ULBD组(111.2 ± 25.0毫升对41.5 ± 22.2毫升,P < 0.05)。OLD组的住院时间(HS)显著长于UBE - ULBD组(6.8 ± 1.6天对4.0 ± 1.4天,P < 0.05)。两组术后VAS、ODI和ZCQ评分均改善。术后1天,UBE - ULBD组的血清肌酸激酶值显著低于OLD组(108.1 ± 11.9对347.0 ± 19.5 U/L,P < 0.05)。1年时,UBE - ULBD组椎旁肌萎缩程度显著低于OLD组(4.50 ± 0.60对11.42 ± 0.87,P < 0.05)。

结论

UBE - ULBD和传统OLD在治疗重度DLSS方面显示出相当的短期临床疗效。然而,与OLD手术相比,UBE - ULBD手术住院时间更短、失血量更少且椎旁肌损伤更小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acfa/9994538/0db9798ed369/fneur-14-1132698-g0001.jpg

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