Belabdelli Fouzia, Bekhti Nabila, Piras Alessandra, Benhafsa Fouad Mekhalef, Ilham Mokhtari, Adil Selka, Anes Lazzaz
Laboratory of Theoretical Chemistry of Bio & Nano-systems, Faculty of Exact Sciences, Djillali Liabes University of Sidi Bel Abbes, Sidi Bel Abbès, Algeria.
Department of Pharmacy, Faculty of Medicine, Djillali Liabes University of Sidi Bel Abbes, Sidi Bel Abbes, Algeria.
Nat Prod Res. 2022 Jun;36(12):3234-3239. doi: 10.1080/14786419.2021.1958215. Epub 2021 Aug 2.
is an important plant of the Rosaceae family, widely used in traditional medicine to treat various conditions such as cardiovascular diseases, cancer, diabetes, asthma, and nephritis. The aim of the current study was to assess the chemical composition, antioxidant, and antibacterial activity of leaves' extracts against The total amounts of polyphenols and flavonoids contained in the dry extracts of plants were estimated by colorimetric methods. DPPH assay was utilized to measure the antioxidant activity of . The phytochemical compounds were determined through HPLC technique, and the minimum inhibitory concentration (MIC) of ethanol extract was performed using the broth dilution method. The ethanol extract represented the richest extract in polyphenol with 473.4mg GAE g and flavonoids 80.9mg CE g and showed considerable antioxidant potential IC =22.50µg/ml. The antibacterial susceptibility test against 0.512mg/mL.
是蔷薇科的一种重要植物，在传统医学中广泛用于治疗各种病症，如心血管疾病、癌症、糖尿病、哮喘和肾炎。本研究的目的是评估叶片提取物的化学成分、抗氧化和抗菌活性。通过比色法估算植物干提取物中多酚和黄酮类化合物的总量。采用DPPH法测定提取物的抗氧化活性。通过HPLC技术测定植物化学成分，并采用肉汤稀释法测定乙醇提取物的最低抑菌浓度（MIC）。乙醇提取物是多酚含量最丰富的提取物，为473.4mg GAE/g，黄酮类化合物含量为80.9mg CE/g，显示出相当大的抗氧化潜力IC50 =22.50µg/ml。对……的抗菌药敏试验为0.512mg/mL。
