Department of General Medicine, Oita University Faculty of Medicine, Japan.
Center for Community Medicine, Oita University Faculty of Medicine, Japan.
Intern Med. 2022 Jan 15;61(2):253-256. doi: 10.2169/internalmedicine.7075-21. Epub 2021 Jul 30.
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV). There is no specific treatment for SFTS, although several reports have indicated that plasma exchange (PE) can be an effective therapy for severe SFTS. However, whether or not PE can reduce the viral load is unclear. We herein report a woman with SFTS who had her SFTSV viral load measured just before and after PE. While the patient recovered, there was no significant difference in the SFTSV viral load after PE. Our results confirmed that PE itself does not reduce the SFTSV viral load.
严重发热伴血小板减少综合征（SFTS）是一种由 SFTS 病毒（SFTSV）引起的新发蜱传感染性疾病。目前尚无针对 SFTS 的特效治疗方法，尽管有报道称，血浆置换（PE）可能是治疗严重 SFTS 的有效方法。然而，PE 是否能降低病毒载量尚不清楚。本文报道了一例 SFTS 患者，在接受 PE 前后对其 SFTSV 病毒载量进行了测量。虽然患者康复，但 PE 后 SFTSV 病毒载量无显著差异。我们的结果证实，PE 本身并不能降低 SFTSV 病毒载量。
