Liu Yan-Wen, Hsu Yung-Tang, Lee Wen-Chin, Tsai Ming-Yen
Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Evid Based Complement Alternat Med. 2021 Jul 13;2021:9953986. doi: 10.1155/2021/9953986. eCollection 2021.
Renal replacement therapy is an important therapy for prolonging life in end-stage renal disease (ESRD) populations, and, in Taiwan, hemodialysis (HD) is the choice for most patients with ESRD. Although HD is effective for prolonging life, it is sometimes associated with complications that patients and doctors have to cope with every day, such as intradialytic hypotension, dialysis disequilibrium syndrome, and muscle cramps. Traditional Chinese medicine (TCM) is a complementary and alternative therapy that has been recognized for its efficacy in treating a variety of diseases by the World Health Organization. Nowadays, the clinical practice of TCM for HD-related complications has received attention for its effectiveness and safety. In this article, we summarize the TCM viewpoint and different TCM interventions for HD-related complications, such as Chinese herbal medicine, acupuncture, herbal acupoint therapy, auricular acupoints, and moxibustion. In the ESRD population, TCM is able to balance Yin and Yang, prevent cardiovascular accidents, control blood pressure, and relieve pain. More importantly, TCM may also improve common HD-related complications such as uremic symptoms, imbalance of electrolyte and fluid status, insomnia, and malnutrition. The mechanism of TCM is considered related to the regulation of autonomous functions and the activation of biologically active chemical substances. According to the studies noted in this review article, TCM has been proven effective for HD-related complications. However, more well-designed and rigorous research will be necessary to reveal the underlying mechanisms in the future.
肾脏替代疗法是延长终末期肾病（ESRD）患者生命的重要疗法，在台湾，血液透析（HD）是大多数ESRD患者的选择。尽管血液透析对延长生命有效，但它有时会引发患者和医生每天都要应对的并发症，如透析中低血压、透析失衡综合征和肌肉痉挛。中医（TCM）是一种补充和替代疗法，其治疗多种疾病的功效已得到世界卫生组织的认可。如今，中医治疗血液透析相关并发症的临床实践因其有效性和安全性而受到关注。在本文中，我们总结了中医对血液透析相关并发症的观点以及不同的中医干预措施，如中药、针灸、中药穴位疗法、耳穴和艾灸。在ESRD患者群体中，中医能够平衡阴阳、预防心血管意外、控制血压和缓解疼痛。更重要的是，中医还可能改善常见的血液透析相关并发症，如尿毒症症状、电解质和液体状态失衡、失眠和营养不良。中医的作用机制被认为与自主功能的调节和生物活性化学物质的激活有关。根据本文综述中提到的研究，中医已被证明对血液透析相关并发症有效。然而，未来还需要更多设计良好且严谨的研究来揭示其潜在机制。
