Rosolanka Robert, Henao-Martinez Andres F, Pisney Larissa, Franco-Paredes Carlos, Krsak Martin
Department of Infectology and Travel Medicine, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, Martin, 036 01, Slovakia.
Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Ther Adv Infect Dis. 2021 Jul 14;8:20499361211032039. doi: 10.1177/20499361211032039. eCollection 2021 Jan-Dec.
Deeper understanding of the spread, morbidity, fatality, and development of immune response associated with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, is necessary in order to establish an appropriate epidemiological and clinical response. Exposure control represents a key part of the combat against COVID-19, as the effectiveness of current therapeutic options remains partial. Since the preventive measures have not been sufficiently able to slow down this pandemic, in this article we explore some of the pertinent knowledge gaps, while overall looking to effective vaccination strategies as a way out. Early on, such strategies may need to rely on counting the convalescents as protected in order to speed up the immunization of the whole population.
为了建立适当的流行病学和临床应对措施,有必要更深入地了解由严重急性呼吸综合征冠状病毒2引起的2019冠状病毒病(COVID-19)的传播、发病率、死亡率以及免疫反应的发展情况。暴露控制是抗击COVID-19的关键部分,因为目前治疗方案的有效性仍然有限。由于预防措施未能充分减缓这一疫情的蔓延,在本文中,我们探讨了一些相关的知识空白,同时全面寻求有效的疫苗接种策略作为解决办法。早期,此类策略可能需要将康复者视为已受保护人群,以便加快整个人口的免疫接种。