Yang Congqi, Park Seongjun
Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141 Republic of Korea.
KAIST Institute for Health Science and Technology (KIHST), Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141 Republic of Korea.
Biomed Eng Lett. 2021 Jun 11;11(3):163-170. doi: 10.1007/s13534-021-00193-w. eCollection 2021 Aug.
Neuromodulation, as a fast-growing technique in neuroscience, has been a great tool in investigation of the neural pathways and treatments for various neurological disorders. However, the limitations such as constricted penetration depth, low temporal resolution and low spatial resolution hindered the development and clinical application of this technique. Nanotechnology, which refers to the technology that deals with dimension under 100 nm, has greatly influenced the direction of scientific researches within recent years. With the recent advancements in nanotechnology, much attention is being given at applying nanomaterials to address the limitations of the current available techniques in the field of biomedical science including neuromodulation. This mini-review aims to introduce the current state-of-the-art stimuli-responsive nanomaterials used for assisting thermally induced neuromodulation.
神经调节作为神经科学领域中一项快速发展的技术,一直是研究神经通路和治疗各种神经系统疾病的重要工具。然而,诸如穿透深度受限、时间分辨率低和空间分辨率低等局限性阻碍了该技术的发展和临床应用。纳米技术是指处理尺寸在100纳米以下的技术,近年来对科学研究的方向产生了重大影响。随着纳米技术的最新进展,人们越来越关注应用纳米材料来解决生物医学科学领域(包括神经调节)中现有技术的局限性。本综述旨在介绍用于辅助热诱导神经调节的当前最先进的刺激响应纳米材料。