Department of Dermatology, Huashan Hospital Affiliated Fudan University, Shanghai, China.
Fetal Medicine Unit &Prenatal Diagnosis Center, Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Ann Palliat Med. 2021 Jul;10(7):8103-8111. doi: 10.21037/apm-21-1738.
The prevalence of vitiligo has been reported to range from 0.1% to 8% worldwide, and vitiligo has been linked to some autoimmune and non-autoimmune diseases. This study aimed to estimate the prevalence of vitiligo and associated comorbidities in adults in Shanghai.
A community-based cross-sectional survey was conducted among 9,114 adults (4,288 males) in a community of Shanghai between October 2009 and January 2010. Face-to-face interviews were conducted at the home of each participant, and all respondents had their skin examined by dermatologists. The risks of comorbidities associated with vitiligo were evaluated by multiple logistic regression analysis.
The estimated prevalence of vitiligo was 0.91%, and the standardized (age-adjusted) prevalence was 0.67%. Prevalence increased with age from 0.20% in 18-30 years to 1.59% in the 71-80 years age group. The presence of vitiligo was associated with increased risks of atopic dermatitis [adjusted odds ratio (aOR) =2.49; 95% confidence interval (95% CI): 1.46-4.23], urticaria (aOR =1.83; 95% CI: 1.11-3.04). and coronary heart disease (aOR =1.88; 95% CI: 1.03-3.41), although the association with coronary heart disease was only identified in subjects who were aged ≥60 years or overweight.
The prevalence of vitiligo in Shanghai was comparable to that seen in previous studies and increased with age. Vitiligo was associated with increased risks of atopic dermatitis, urticaria, and coronary heart disease in adults.
据报道，全球范围内白癜风的患病率为 0.1%至 8%，并且白癜风与一些自身免疫性和非自身免疫性疾病有关。本研究旨在估计上海成年人白癜风的患病率及相关合并症。
2009 年 10 月至 2010 年 1 月期间，在上海的一个社区中对 9114 名成年人（4288 名男性）进行了一项基于社区的横断面调查。在每个参与者的家中进行面对面访谈，并且所有受访者都由皮肤科医生进行了皮肤检查。通过多因素逻辑回归分析评估了与白癜风相关的合并症的风险。
估计白癜风的患病率为 0.91%，标准化（年龄调整）患病率为 0.67%。患病率随年龄增长而增加，从 18-30 岁的 0.20%增加到 71-80 岁年龄组的 1.59%。患有白癜风与特应性皮炎（调整后的优势比[aOR] =2.49；95%置信区间[95%CI]：1.46-4.23）、荨麻疹（aOR =1.83；95%CI：1.11-3.04）和冠心病（aOR =1.88；95%CI：1.03-3.41）的风险增加有关，尽管与冠心病的关联仅在年龄≥60 岁或超重的受试者中被发现。
上海白癜风的患病率与以往研究相似，且随年龄增长而增加。白癜风与成年人特应性皮炎、荨麻疹和冠心病的风险增加有关。
