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用于客观评估面部白癜风患者临床治疗效果的Antera 3D皮肤图像分析系统。

Antera 3D skin image analysis system for objective evaluation of clinical treatment efficacy in a patient with facial vitiligo.

作者信息

Han Liu, Jinzhu Yang, Xiuyun Huang, Zhen Yi, Yinying Rao, Jiyu Li, Miao Qu, Xingping Quan, Mudiao Chen, Jinlian Feng, Yongbin Qu

机构信息

The Physiotherapy Department, Dermatology Hospital of Southern Medical University, Guangzhou, 510091, China.

Nursing department, Dermatology Hospital of Southern Medical University, Guangzhou, 510091, China.

出版信息

Arch Dermatol Res. 2025 Mar 18;317(1):594. doi: 10.1007/s00403-025-03941-5.

DOI:10.1007/s00403-025-03941-5
PMID:40100282
Abstract

OBJECTIVE

To evaluate the changes of skin surface parameters in a patient with vitiligo using Antera 3D Skin Image Analysis System, and to observe the clinical efficacy of the treatment of facial vitiligo.

METHODS

A patient with facial vitiligo was treated with intradermal injection of psoralen solution into the lesion combined with 308 nm excimer laser therapy. Vitiligo lesion images were captured using the Antera 3D camera before treatment and every 2 weeks after the start of the treatment. The associated software analysis system was used to measure the parameters of melanin level, ultra-low melanin concentration, and L* value as objective indexes for the evaluation of vitiligo treatment efficacy.

RESULTS

After 10 treatments, the melanin level of the patient's skin lesions increased from 0.480 to 0.580, while the ultra-low melanin concentration and L* value decreased from 9.360 to 64.10 to 3.032 and 58.10, respectively.

CONCLUSION

The Antera 3D skin image analysis system provides objective data, which are conducive to improving patients' treatment compliance and confidence, as well as facilitating the development of treatment plans.

摘要

目的

使用Antera 3D皮肤图像分析系统评估白癜风患者皮肤表面参数的变化,并观察面部白癜风的治疗临床疗效。

方法

一名面部白癜风患者采用病变部位皮内注射补骨脂素溶液联合308 nm准分子激光治疗。在治疗前及治疗开始后每2周使用Antera 3D相机采集白癜风病变图像。使用相关软件分析系统测量黑色素水平、超低黑色素浓度和L*值等参数,作为评估白癜风治疗效果的客观指标。

结果

经过10次治疗后,患者皮肤病变的黑色素水平从0.480增加到0.580,而超低黑色素浓度和L*值分别从9.360和64.10下降到3.032和58.10。

结论

Antera 3D皮肤图像分析系统提供了客观数据,有利于提高患者的治疗依从性和信心,并有助于制定治疗方案。

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本文引用的文献

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Scientific validation of clinical visual scales and Antera 3D™ consistency with derived measurements in the assessment of infantile haemangioma after laser therapy.临床视觉量表的科学验证以及在激光治疗后婴儿血管瘤评估中Antera 3D™与衍生测量的一致性
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Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the international Vitiligo Task Force-Part 2: Specific treatment recommendations.全球白癜风诊断和治疗专家建议:国际白癜风特别工作组立场声明-第 2 部分:具体治疗建议。
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Clinician-reported outcome measures for the assessment of vitiligo: A scoping review.
临床医生报告的用于评估白癜风的结局测量指标:范围综述。
J Eur Acad Dermatol Venereol. 2023 Nov;37(11):2231-2242. doi: 10.1111/jdv.19448. Epub 2023 Sep 11.
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Comparison of Antera 3D® and TcPO2 for Evaluation of Blood Flow in Skin.用于评估皮肤血流的Antera 3D®与经皮氧分压(TcPO2)的比较
Yonago Acta Med. 2023 Feb 10;66(1):146-152. doi: 10.33160/yam.2023.02.016. eCollection 2023 Feb.
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Efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of keloid: A randomized controlled trial.创新型冷大气压等离子体技术治疗瘢痕疙瘩的疗效与安全性:一项随机对照试验。
J Cosmet Dermatol. 2022 Dec;21(12):6788-6797. doi: 10.1111/jocd.15397. Epub 2022 Oct 14.
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Vitiligo prevalence and quality of life among adults in Europe, Japan and the USA.白癜风在欧洲、日本和美国成年人中的患病率和生活质量。
J Eur Acad Dermatol Venereol. 2022 Oct;36(10):1831-1844. doi: 10.1111/jdv.18257. Epub 2022 Jun 14.
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Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract.应用含葡萄籽提取物的防晒配方后亚洲人皮肤变化的临床研究。
J Cosmet Dermatol. 2022 Oct;21(10):4523-4535. doi: 10.1111/jocd.14982. Epub 2022 May 2.
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VAS and NRS, Same or Different? Are Visual Analog Scale Values and Numerical Rating Scale Equally Viable Tools for Assessing Patients after Microdiscectomy?VAS 和 NRS,相同还是不同?视觉模拟评分法和数字评分法在评估微创椎间盘切除术患者时同样可行吗?
Pain Res Manag. 2022 Mar 29;2022:5337483. doi: 10.1155/2022/5337483. eCollection 2022.
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S1-Leitlinie: Diagnostik und Therapie der Vitiligo.S1指南:白癜风的诊断与治疗
J Dtsch Dermatol Ges. 2022 Mar;20(3):365-379. doi: 10.1111/ddg.14713_g.
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Prevalence of vitiligo and associated comorbidities in adults in Shanghai, China: a community-based, cross-sectional survey.中国上海成年人白癜风的患病率及相关合并症:一项基于社区的横断面调查。
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