Schlitter Anna Melissa, Häberle Lena, Richter Caroline, Huss Ralf, Esposito Irene
Institut für Allgemeine Pathologie und Pathologische Anatomie, Technische Universität München, Trogerstr. 18, 81675, München, Deutschland.
Institut für Pathologie, Heinrich-Heine-Universität und Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Pathologe. 2021 Sep;42(5):453-463. doi: 10.1007/s00292-021-00971-4. Epub 2021 Aug 6.
Most pancreatic ductal adenocarcinomas are localized in the pancreatic head. Due to the complex anatomic relationships with the surrounding organs and vascular structures in the retroperitoneal space and to the presence of numerous transection margins and dissection planes, pancreatic head resections belong to the most complex specimens concerning grossing and sampling for histopathologic analysis.Here we discuss current guidelines for standardized grossing and reporting of pancreatic cancer, with special reference to the assessment of the resection margin status. The importance of standardized reporting for the sake of completeness, comprehensibility, comparability, and quality control as well as for the integration of pathology reports in interdisciplinary digital workflows and artificial intelligence applications will be emphasized.
大多数胰腺导管腺癌位于胰头。由于与腹膜后间隙周围器官和血管结构的解剖关系复杂，且存在众多横断边缘和解剖平面，胰头切除术属于组织病理学分析中取材和采样最复杂的标本。在此，我们讨论胰腺癌标准化取材和报告的现行指南，特别提及切缘状态的评估。将强调标准化报告对于完整性、可理解性、可比性和质量控制的重要性，以及在跨学科数字工作流程和人工智能应用中整合病理报告的重要性。
