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补充天然化合物在脑卒中患者中的作用。

The Role of Supplementation with Natural Compounds in Post-Stroke Patients.

机构信息

Biohazard Prevention Centre, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.

Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.

出版信息

Int J Mol Sci. 2021 Jul 23;22(15):7893. doi: 10.3390/ijms22157893.

Abstract

Malnutrition is a serious problem in post-stroke patients. Importantly, it intensifies with hospitalization, and is related to both somatic and psychological reasons, as well as is associated with the insufficient knowledge of people who accompany the patient. Malnutrition is a negative prognostic factor, leading to a reduction in the quality of life. Moreover, this condition significantly extends hospitalization time, increases the frequency of treatment in intensive care units, and negatively affects the effectiveness of rehabilitation. Obtaining growing data on the therapeutic effectiveness of new compounds of natural origin is possible through the use of pharmacodynamic and analytical methods to assess their therapeutic properties. The proper supply of nutrients, as well as compounds of natural origin, is an important element of post-stroke therapy, due to their strong antioxidant, anti-inflammatory, neuroprotective and neuroplasticity enhancing properties. Taking the above into account, in this review we present the current state of knowledge on the benefits of using selected substances of natural origin in patients after cerebral stroke.

摘要

营养不良是脑卒中患者的一个严重问题。重要的是,随着住院时间的延长,它会加剧,这与躯体和心理原因有关,也与陪伴患者的人的知识不足有关。营养不良是一个负面的预后因素,导致生活质量下降。此外,这种情况还显著延长了住院时间,增加了重症监护病房治疗的频率,并对康复效果产生负面影响。通过使用药效学和分析方法来评估其治疗特性,可以获得关于天然来源新化合物治疗效果的越来越多的数据。适当提供营养物质以及天然来源的化合物是脑卒中后治疗的一个重要元素,因为它们具有很强的抗氧化、抗炎、神经保护和增强神经可塑性的特性。考虑到这一点,在这篇综述中,我们介绍了目前关于在脑卒中后患者中使用选定天然来源物质的益处的知识现状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3df/8348438/add2ca68495b/ijms-22-07893-g001.jpg

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