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一种与疟疾相关的罕见黄斑病变。

An unusual macular lesion associated with malaria.

作者信息

Runyan T E, Ostberg R C

出版信息

Ann Ophthalmol. 1977 Dec;9(12):1521-5.

PMID:343689
Abstract

A case of a young man afflicted with falciparum malaria is presented in which the primary ocular finding was a subpigment epithelial hemorrhage involving the macula. Previous reports in the literature concentrate on peripheral and central retinal hemorrhages, almost to the exclusion of choroidal vascular abnormalities. The value of this case lies in the recognition that the choroid can assume an important role in fundus abnormalities associated with malaria, probably on the basis of obstructive phenomena with subsequent ischemic degenerative changes, similar to the process which involves the retinal vessels and central nervous system.

摘要

本文报告一例年轻的恶性疟患者,其主要眼部表现为累及黄斑的色素上皮下出血。文献中既往报道主要集中于周边及中心视网膜出血,几乎未涉及脉络膜血管异常。该病例的价值在于认识到脉络膜在与疟疾相关的眼底异常中可能起重要作用,这可能是基于阻塞现象及随后的缺血性退行性改变,类似于累及视网膜血管和中枢神经系统的过程。

相似文献

1
An unusual macular lesion associated with malaria.一种与疟疾相关的罕见黄斑病变。
Ann Ophthalmol. 1977 Dec;9(12):1521-5.
2
Coagulative necrosis in a malignant melanoma of the choroid at the macula with extensive subretinal hemorrhage.黄斑部脉络膜恶性黑色素瘤伴广泛视网膜下出血的凝固性坏死。
Invest Ophthalmol. 1973 Jul;12(7):525-31.
3
[Malaria tropica with macular hemorrhage].
Ophthalmologica. 1987;195(3):141-4. doi: 10.1159/000309803.
4
[X-shaped macular hemorrhage disclosing mixed occlusion of the cilioretinal artery and central retinal vein].[X形黄斑出血提示睫状视网膜动脉与视网膜中央静脉混合性阻塞]
J Fr Ophtalmol. 1994;17(2):133-7.
5
[Malaria and retinal hemorrhages].
Med Trop (Mars). 1990 Apr;50(2):197-9.
6
Idiopathic polypoidal choroidal vasculopathy of the macula.特发性黄斑息肉样脉络膜血管病变
Ophthalmology. 1998 Aug;105(8):1380-5. doi: 10.1016/S0161-6420(98)98016-2.
7
Evidence for vasculitis in acute posterior multifocal placoid pigment epitheliopathy.急性后极部多灶性鳞状色素上皮病变中血管炎的证据。
Ann Ophthalmol. 1979 Apr;11(4):539-42.
8
[A case of multiple epitheliopathy associated with sub-retinal neovascularization].[一例与视网膜下新生血管形成相关的多发性上皮病变]
J Fr Ophtalmol. 1988;11(2):191-4.
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[Idiopathic central serous chorioretinopathy].[特发性中心性浆液性脉络膜视网膜病变]
J Fr Ophtalmol. 1984;7(5):419-36.
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Ophthalmoscopic findings in adult patients with severe falciparum malaria.成年重症恶性疟患者的眼底镜检查结果
Ocul Immunol Inflamm. 2008 Sep-Oct;16(5):239-41. doi: 10.1080/09273940802409977.

引用本文的文献

1
Retinal Hemorrhages in Severe Non-cerebral Plasmodium vivax Malaria in an Adult.成人严重间日疟原虫非脑型疟疾中的视网膜出血
J Clin Diagn Res. 2015 Jun;9(6):OD01-3. doi: 10.7860/JCDR/2015/11930.6003. Epub 2015 Jun 1.
2
Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria.加纳儿童严重疟疾性视网膜病变——脑性疟疾和非脑性疟疾眼底改变的重叠。
Malar J. 2010 Aug 12;9:232. doi: 10.1186/1475-2875-9-232.
3
Retinal hemorrhage in Plasmodium vivax malaria.间日疟原虫疟疾中的视网膜出血。
Am J Trop Med Hyg. 2010 Feb;82(2):219-22. doi: 10.4269/ajtmh.2010.09-0439.