Tashiro K, Matsumoto A, Hamada T, Moriwaka F
Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan.
J Neurol Neurosurg Psychiatry. 1987 Dec;50(12):1572-8. doi: 10.1136/jnnp.50.12.1572.
Twenty-eight cases of mirror writing were seen during a period of three and a half years. These consisted of 12 patients with essential tremor, nine with Parkinson's disease, three with spino-cerebellar degeneration and four other cases. There were no cases of hemiparesis, aphasia, apraxia, agnosia or confusion. Fragmentary reversals were excluded from this study. Since essential tremor, Parkinsonian tremor and cerebellar tremor can be abolished by a stereotaxic produce applied to the thalamus, a common neural pathway via the thalamic nuclei may exist in these disorders. The existence is therefore proposed of some neural mechanism that controls the higher cerebral function of writing via the thalamus.
在三年半的时间里共观察到28例镜像书写病例。其中包括12例特发性震颤患者、9例帕金森病患者、3例脊髓小脑变性患者以及其他4例。没有偏瘫、失语、失用症、失认症或意识模糊的病例。本研究排除了部分反转的情况。由于应用于丘脑的立体定向手术可消除特发性震颤、帕金森震颤和小脑震颤,因此这些疾病可能存在一条经丘脑核团的共同神经通路。因此有人提出,存在某种通过丘脑控制书写高级脑功能的神经机制。