检测染色质可及性：ATAC-seq 技术。
Measuring Chromatin Accessibility: ATAC-Seq.
机构信息
Salk Institute for Biological Studies, La Jolla, CA, USA.
Institute of Molecular Biology (IMB), Mainz, Germany.
出版信息
Methods Mol Biol. 2021;2351:105-121. doi: 10.1007/978-1-0716-1597-3_6.
PMID:34382186
Abstract
Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq) is a method to investigate the accessibility of chromatin in a genome-wide fashion. In this chapter, we provide a brief history of the chromatin accessibility field followed by a detailed protocol to perform ATAC-Seq assay.
摘要
利用测序进行转座酶可及染色质分析（ATAC-Seq）是一种全面研究基因组中染色质可及性的方法。在本章中，我们首先简要介绍染色质可及性领域的历史，然后详细介绍 ATAC-Seq 检测的实验方案。
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