Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of the Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, PR China.
Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of the Ministry of Agriculture, Huazhong Agricultural University, Wuhan 430070, PR China.
Meat Sci. 2022 Jan;183:108642. doi: 10.1016/j.meatsci.2021.108642. Epub 2021 Aug 6.
Improving meat quality is a crucial purpose of commercial production and breeding systems. In this study, multiomics techniques were used to investigate the molecular mechanisms that impact the excessive diversity of meat quality in Enshi black pigs. The results suggest that 120 differentially expressed genes (DEGs) and 171 significantly changed metabolites (SCMs) contribute to the content of intramuscular fat (IMF) through the processes of fat accumulation and regulation of lipolysis. A total of 141 DEGs and 47 SCMs may regulate meat color through the processes of nicotinate and nicotinamide metabolism. Herein, we found some candidate genes associated with IMF and meat color. We also presented a series of metabolites that are potentially available biological indicators to measure meat quality. This research provides further insight into the detection of intramuscular fat accumulation and meat color variation and provides a reference for molecular mechanisms in the regulation of IMF and meat color.
提高肉质是商业生产和养殖系统的一个关键目的。在这项研究中，多组学技术被用于研究影响恩施黑猪肉质过度多样性的分子机制。结果表明，120 个差异表达基因（DEGs）和 171 个显著变化代谢物（SCMs）通过脂肪积累和脂解调节过程影响肌内脂肪（IMF）的含量。共有 141 个差异表达基因和 47 个显著变化代谢物可能通过烟碱酸和烟酰胺代谢过程调节肉色。在这里，我们发现了一些与 IMF 和肉色相关的候选基因。我们还提出了一系列可能作为生物指标来衡量肉质的代谢物。本研究为肌内脂肪积累和肉色变化的检测提供了更深入的了解，并为 IMF 和肉色调节的分子机制提供了参考。
