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评估脱敏牙膏对牙本质过敏管理的疗效:扫描电子显微镜分析

Evaluating the efficacy of desensitizing dentifrices on dentinal hypersensitivity management: A scanning electron microscopic analysis.

作者信息

Midha Vasu, Midha Vishu, Kochhar Anuraj Singh, Kochhar Gulsheen Kaur, Bhasin Ritasha, Dadlani Himanshu

机构信息

Department of Endodontics, National Dental College and Hospital, Dera Bassi, Punjab, India.

Department of Pediatric and Preventive Dentistry, National Dental College and Hospital, Dera Bassi, Punjab, India.

出版信息

J Indian Soc Periodontol. 2021 Jul-Aug;25(4):283-287. doi: 10.4103/jisp.jisp_247_20. Epub 2021 Jul 1.

Abstract

INTRODUCTION

Dentin hypersensitivity (DH) adversely affects quality of life by impairing the ability to eat and drink certain foods, therefore, should be addressed promptly with a contingency plan that includes initial treatment with a noninvasive prophylactic home care approach, followed by in-office treatment if desired result is not achieved.

AIM

The purpose of this study was to evaluate the effectiveness of four different pastes containing 5% NovaMin (Sensodyne Repair and Protect), Propolis (Phytoshield Propolis), 5% potassium nitrate (Sensodyne), and 8% arginine (Colgate Sensitive Pro Relief) based toothpastes in the treatment of DH.

MATERIALS AND METHODS

One hundred dentin slices were cut from the crown section of molars. Etching with 37% orthophosphoric acid was done to open the tubules. Scanning electron microscope (SEM) study was done to ensure that the tubules are opened. The dentin specimens were divided into four groups: Group 1 -5% NovaMin, Group 2 - Propolis, Group 3 - 5% potassium nitrate, and Group 4 - 8% arginine. Samples were brushed for 2 min twice daily with a soft toothbrush for 15 days and were stored in distilled water. The samples were rinsed under running water to remove the toothpaste. The SEM was performed to check the obliteration of tubules.

RESULTS

5% NovaMin group showed more completely occluded dentinal tubules when compared to other groups. The differences among all the groups were statistically significant ( ≤ 0.05).

CONCLUSION

In the present study, all materials, NovaMin, Propolis, potassium nitrate, and arginine, were effective in occluding dentinal tubules but NovaMin appeared most proficient in occluding tubules, followed by arginine, potassium nitrate, and Propolis. Topical NovaMin is an upcoming agent demonstrating desensitization and remineralization properties.

摘要

引言

牙本质过敏症(DH)会影响进食和饮用某些食物的能力,从而对生活质量产生不利影响,因此,应迅速制定应急计划进行处理,该计划包括采用无创预防性家庭护理方法进行初始治疗,若未达到预期效果则进行门诊治疗。

目的

本研究旨在评估四种不同的含5%诺瓦敏(舒适达修复防护牙膏)、蜂胶(植益蜂胶牙膏)、5%硝酸钾(舒适达牙膏)和8%精氨酸(高露洁敏感专业修复牙膏)的牙膏在治疗牙本质过敏症方面的效果。

材料与方法

从磨牙冠部切取100片牙本质切片。用37%的正磷酸进行酸蚀以开放牙本质小管。进行扫描电子显微镜(SEM)研究以确保牙本质小管已开放。将牙本质标本分为四组:第1组 - 5%诺瓦敏,第2组 - 蜂胶,第3组 - 5%硝酸钾,第4组 - 8%精氨酸。用软牙刷每天两次对样本刷牙2分钟,持续15天,并保存在蒸馏水中。将样本在流水下冲洗以去除牙膏。进行扫描电子显微镜检查以检查牙本质小管的封闭情况。

结果

与其他组相比,5%诺瓦敏组显示牙本质小管封闭更完全。所有组之间的差异具有统计学意义(≤0.05)。

结论

在本研究中,所有材料,诺瓦敏、蜂胶、硝酸钾和精氨酸,在封闭牙本质小管方面均有效,但诺瓦敏在封闭小管方面似乎最为有效,其次是精氨酸、硝酸钾和蜂胶。局部应用诺瓦敏是一种具有脱敏和再矿化特性的新兴药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbb/8336776/c836e68e0231/JISP-25-283-g001.jpg

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