Beijing Ruijing Diabetes Hospital, Beijing.
Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University.
Medicine (Baltimore). 2021 Jul 30;100(30):e26722. doi: 10.1097/MD.0000000000026722.
To evaluate the atherosclerotic cardiovascular diseases (ASCVD) risk factors in type 2 diabetes patients from the primary diabetes clinics for further comprehensive intervention in China.A cross-sectional study was conducted in 5 primary diabetes chain hospitals in Beijing, Lanzhou, Harbin, Chengdu, and Taiyuan in continuous patients with type 2 diabetes from March 2016 to December 2019. The data collected at the first visit were analyzed, and proportions of patients reached the targets (glycosylated hemoglobin [HbA1c] < 7%, blood pressure < 130/80 mm Hg, and low-density lipoprotein cholesterol [LDL-C] < 2.6mmol/l) were calculated. The clinical characteristics and the associated factors with achievement in HbA1c, blood pressure, and LDL-C targets were analyzed.A total of 20,412 participants, including 11,353 men (55.6%), with an average age of (59.4 ± 10.4) years were enrolled. Nearly 95% diabetes had one or more ASCVD risk factors other than hyperglycemia. The control rates of HbA1c, blood pressure, and LDL-C were 26.5%, 27.8%, and 42.6%, respectively. Only 4.1% patients achieved all 3 targets. Nearly 95% patients had one or more ASCVD risk factors other than hyperglyciemia. Diabetes duration, family history, and overweight/obesity were associated with the number of aggregated ASCVD risk factors. The patients with older age, no overweight/obesity, not smoking, less ASCVD risk factors, and having special diabetes care insurance (Chengdu) were associated with a higher control rates.To deal with poor control status, global management of ASCVD risk factors, weight loss, and smoking cessation must be emphasized in the primary diabetes care settings. Special diabetes care insurance should be advocated.Current ClinicalTrial.gov protocol ID NCT03707379. Date of Registration: October 16, 2018. https://clinicaltrials.gov.
评估中国二甲医院 2 型糖尿病患者的动脉粥样硬化性心血管疾病(ASCVD)危险因素,以便进行进一步的综合干预。本研究采用横断面研究,纳入 2016 年 3 月至 2019 年 12 月期间来自北京、兰州、哈尔滨、成都和太原 5 家糖尿病链式医院的连续就诊的 2 型糖尿病患者。分析首次就诊时采集的数据,计算达到目标(糖化血红蛋白[HbA1c]<7%、血压<130/80mmHg 和低密度脂蛋白胆固醇[LDL-C]<2.6mmol/L)的患者比例。分析达到 HbA1c、血压和 LDL-C 目标的患者的临床特征及相关因素。共纳入 20412 名参与者,其中男性 11353 名(55.6%),平均年龄(59.4±10.4)岁。近 95%的糖尿病患者除高血糖外,还存在一种或多种 ASCVD 危险因素。HbA1c、血压和 LDL-C 的控制率分别为 26.5%、27.8%和 42.6%,仅有 4.1%的患者达到 3 个目标。近 95%的糖尿病患者除高血糖外,还存在一种或多种 ASCVD 危险因素。糖尿病病程、家族史和超重/肥胖与 ASCVD 危险聚集因素的数量相关。年龄较大、无超重/肥胖、不吸烟、ASCVD 危险因素较少和参加特殊糖尿病医疗保险(成都)的患者与更高的控制率相关。为改善控制不佳的现状,在基层糖尿病管理中必须强调 ASCVD 危险因素的全面管理、减重和戒烟。应提倡特殊的糖尿病医疗保险。当前临床试验.gov 方案 ID:NCT03707379。注册日期:2018 年 10 月 16 日。https://clinicaltrials.gov。