Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Cold Spring Harb Perspect Biol. 2022 May 27;14(5):a039859. doi: 10.1101/cshperspect.a039859.
Auxin has always been at the forefront of research in plant physiology and development. Since the earliest contemplations by Julius von Sachs and Charles Darwin, more than a century-long struggle has been waged to understand its function. This largely reflects the failures, successes, and inevitable progress in the entire field of plant signaling and development. Here I present 14 stations on our long and sometimes mystical journey to understand auxin. These highlights were selected to give a flavor of the field and to show the scope and limits of our current knowledge. A special focus is put on features that make auxin unique among phytohormones, such as its dynamic, directional transport network, which integrates external and internal signals, including self-organizing feedback. Accented are persistent mysteries and controversies. The unexpected discoveries related to rapid auxin responses and growth regulation recently disturbed our contentment regarding understanding of the auxin signaling mechanism. These new revelations, along with advances in technology, usher us into a new, exciting era in auxin research.
生长素一直处于植物生理学和发育研究的前沿。自朱利叶斯·冯·萨克斯和查尔斯·达尔文最早的思考以来，人们已经进行了一个多世纪的努力来理解它的功能。这在很大程度上反映了整个植物信号转导和发育领域的失败、成功和不可避免的进展。在这里，我介绍了我们在理解生长素的漫长而有时神秘的旅程中的 14 个站点。这些亮点的选择是为了给该领域一个风味，并展示我们当前知识的范围和局限性。特别关注的是使生长素在植物激素中独一无二的特征，例如其动态、有方向的运输网络，它整合了外部和内部信号，包括自组织反馈。强调的是持久的谜团和争议。最近与快速生长素反应和生长调控相关的意外发现扰乱了我们对生长素信号转导机制理解的满足感。这些新的发现，以及技术的进步，将我们带入了生长素研究的一个新的、令人兴奋的时代。
