Wageningen Food and Biobased Research, Wageningen University and Research, Wageningen, The Netherlands.
Biometris, Wageningen University & Research, Wageningen, The Netherlands.
Int J Food Sci Nutr. 2022 Mar;73(2):251-262. doi: 10.1080/09637486.2021.1960958. Epub 2021 Aug 18.
A human intervention trial was conducted to study amino acid uptake of the novel Lemna protein concentrate (LPC) in comparison to whey (WPC). The study was a cross-over, double-blind, controlled trial in which 12 healthy participants received 20 grams of LPC and WPC in randomised order. The LPC consumption resulted in a significant lower postprandial increase in almost all individual amino acids, total amino acid (TAA) and total essential amino acids (TEAA) compared to WPC based on area under the curve (AUC) calculations. When the AUC after WPC consumption was set at 100%, LPC showed a relative AUC of 60.4% for TAA and 66.3% for the TEAA. Interindividual variation for LPC was high with an uptake of TEAA of LPC compared to WPC ranging from 18.2 to 94.2%. Human intervention trials can partly replace animal trials as they fully reflect the human situation and provide estimates on individual variations.
一项人体干预试验旨在研究新型浮萍蛋白浓缩物（LPC）与乳清（WPC）的氨基酸吸收情况。该研究为交叉、双盲、对照试验，12 名健康参与者随机接受 20 克 LPC 和 WPC。基于曲线下面积（AUC）计算，与 WPC 相比，LPC 摄入后几乎所有单个氨基酸、总氨基酸（TAA）和总必需氨基酸（TEAA）的餐后增加幅度明显较低。当 WPC 消耗后的 AUC 设定为 100%时，LPC 的 TAA 和 TEAA 的相对 AUC 分别为 60.4%和 66.3%。LPC 的个体间变异较大，与 WPC 相比，LPC 的 TEAA 吸收率范围为 18.2%至 94.2%。人体干预试验可以部分替代动物试验，因为它们完全反映了人体情况，并提供了个体变异的估计。
