Yee Loh S, Zakaria Rosnani, Mohamad Noraini, Fong Ong W
Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
Department of Medicine, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.
J Taibah Univ Med Sci. 2021 Jan 29;16(4):632-636. doi: 10.1016/j.jtumed.2021.01.001. eCollection 2021 Aug.
Non-gestational choriocarcinoma of the ovary is an extremely rare clinical condition. Very few cases of this high-grade malignancy of the ovary are reported in the literature worldwide. Given the rarity of the tumour, this disease is generally overlooked, which leads to delayed diagnosis and management. For the attending clinicians, the non-gestational choriocarcinoma of the ovary poses a diagnostic challenge due to its non-specific clinical presentations. A 16-year-old girl presented with pain in the right iliac fossa and with a positive urine pregnancy test. Despite being sexually inactive, the patient was diagnosed with an ectopic pregnancy and underwent emergency laparoscopic surgery. Six weeks later, the histopathological analysis revealed a diagnosis of non-gestational choriocarcinoma of the ovary. Further evaluations showed that her cancer had already advanced to stage IV. In this case report, the non-specific presentations of the disease, radiological features, current treatments, and possible safety strategies are discussed.
卵巢非妊娠性绒毛膜癌是一种极为罕见的临床病症。全球范围内的文献中报道的这种卵巢高级别恶性肿瘤的病例极少。鉴于该肿瘤的罕见性，这种疾病通常被忽视，从而导致诊断和治疗延迟。对于主治医生而言，卵巢非妊娠性绒毛膜癌因其非特异性临床表现而带来诊断挑战。一名16岁女孩出现右下腹疼痛，尿妊娠试验呈阳性。尽管该患者无性活动史，但仍被诊断为异位妊娠并接受了急诊腹腔镜手术。六周后，组织病理学分析显示诊断为卵巢非妊娠性绒毛膜癌。进一步评估表明，她的癌症已进展至IV期。在本病例报告中，讨论了该疾病的非特异性表现、放射学特征、当前治疗方法以及可能的安全策略。
