Chu Sherman, Mehrmal Sino, Uppal Prabhdeep, Giesey Rachel L, Delost Maria E, Delost Gregory R
College of Osteopathic Medicine of the Pacific Northwest, Western University of Health Sciences, Lebanon, Oregon.
Arizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona.
JAAD Int. 2020 Jul 28;1(2):95-103. doi: 10.1016/j.jdin.2020.07.001. eCollection 2020 Dec.
Dermatoses contribute to a large burden of global disease, but the relationship between socioeconomic status and the effect of dermatologic conditions in Europe is not well understood.
We selected Global Burden of Disease Study data sets to analyze disability-adjusted life-years (DALYs) and the annual rate of change of dermatoses between 1990 and 2017 in 43 European countries. The principal country-level economic factor used was gross domestic product per capita from the World Bank. Statistical analysis was performed with Spearman ρ correlation.
Wealthier European countries had higher DALYs for melanoma, basal cell carcinoma, psoriasis, atopic dermatitis, acne, seborrheic dermatitis, alopecia, asthma, contact dermatitis, and viral skin disease. Poorer countries had higher DALYs of squamous cell carcinoma, urticaria, decubitus ulcers, pruritus, scabies, tuberculosis, and syphilis. Thirteen European countries were in the top 10th percentile globally for annual increase in skin and subcutaneous disease burden.
The majority of European countries have experienced an increase in skin and subcutaneous diseases in recent decades relative to the rest of the world, but the burden of individual dermatoses in Europe varies by country and socioeconomic status. DALYs can potentially serve as a purposeful measure for directing resources to improve the burden of skin disease in Europe.
皮肤病给全球疾病带来了沉重负担，但欧洲社会经济地位与皮肤病状况影响之间的关系尚不清楚。
我们选取了全球疾病负担研究数据集，以分析1990年至2017年43个欧洲国家皮肤病的伤残调整生命年（DALYs）和年变化率。所使用的主要国家层面经济因素是世界银行的人均国内生产总值。采用Spearman ρ相关性进行统计分析。
较富裕的欧洲国家在黑色素瘤、基底细胞癌、银屑病、特应性皮炎、痤疮、脂溢性皮炎、脱发、哮喘、接触性皮炎和病毒性皮肤病方面的伤残调整生命年较高。较贫穷的国家在鳞状细胞癌、荨麻疹、压疮、瘙痒症、疥疮、结核病和梅毒方面的伤残调整生命年较高。13个欧洲国家在皮肤和皮下疾病负担的年度增加方面位居全球前10%。
近几十年来，相对于世界其他地区，大多数欧洲国家的皮肤和皮下疾病有所增加，但欧洲各国皮肤病的负担因国家和社会经济地位而异。伤残调整生命年有可能作为一种有针对性的衡量标准，用于指导资源分配以改善欧洲皮肤病的负担。
