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Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico.墨西哥大型数据集内 COVID-19 患者的临床特征和死亡风险因素。
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印度尼西亚中爪哇省的新冠肺炎死亡病例及相关人口统计学因素

COVID-19 deaths and associated demographic factors in Central Java, Indonesia.

作者信息

Sutiningsih Dwi, Azzahra Nur Azizah, Prabowo Yulianto, Sugiharto Aris, Wibowo Mufti Agung, Lestari Endah Sri, Aurorina Estri

机构信息

DVM, M.PH, Ph.D., Epidemiology and Tropical Disease Department, Public Health Faculty, Diponegoro University, Prof. Soedarto, S.H., Tembalang Street, Semarang, Central Java, Indonesia, 50275, and Master of Epidemiology, Postgraduate School, Diponegoro University, Imam Bardjo S.H., No.5 Street, Semarang, Central Java, Indonesia, 50241.

BPH, Master of Epidemiology, Postgraduate School, Diponegoro University, Imam Bardjo S.H., No.5 Street, Semarang, Central Java, Indonesia, 50241.

出版信息

Germs. 2021 Jun 2;11(2):255-265. doi: 10.18683/germs.2021.1262. eCollection 2021 Jun.

DOI:10.18683/germs.2021.1262
PMID:34422697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8373415/
Abstract

INTRODUCTION

To date, the total number of COVID-19 deaths is still increasing, including in Central Java, with the third-highest total number of deaths in Indonesia. There are still limited studies related to the cases of COVID-19. Thus, this study's objective was to provide an overview of the characteristics of 4359 COVID-19 death cases in Central Java.

METHODS

This research used a cross-sectional descriptive design with univariate, bivariate, and multivariate analysis involving secondary data acquired from a report by the Provincial Health Office of Central Java, recorded up to 13 December 2020.

RESULTS

The results showed that the highest frequencies of death cases were contributed from ≥60 years group (n=1897 patients; 43.52%) and the male (n=2497 patients; 57.28%) group. The case fatality rate (CFR) rose with age, and the highest CFR was recorded in the elderly (17.95%), males (7.60%), in Pati District (17.45%), while entrepreneur (14.64%) was the highest reported job. Furthermore, the eldest group (≥60 years) and males were more susceptible to die, with ORs 5.49 (95%CI: 5.15-5.86) and 1.61 (95%CI: 1.51-1.71), sequentially. The majority of death cases had comorbidities (65.79%), while the most prevalent reported comorbidities were diabetes (n=1387, 31.82%) and hypertension (n=817, 18.74%). Meanwhile, patients of old age were more likely to associate comorbidity, p<0.001, OR 1.664 (95%CI: 1.425-1.944).

CONCLUSIONS

This study concludes that patients of older age and males may become more vulnerable than younger and females to experience death. Further study is required to measure the relationship between other characteristics of demographics, underlying medical conditions, and fatality.

摘要

引言

截至目前,新冠病毒病死亡总数仍在上升,中爪哇省也不例外,该省的死亡总数在印度尼西亚位列第三。关于新冠病毒病病例的研究仍然有限。因此,本研究的目的是概述中爪哇省4359例新冠病毒病死亡病例的特征。

方法

本研究采用横断面描述性设计,进行单变量、双变量和多变量分析,所涉及的二手数据来自中爪哇省卫生厅的一份报告,记录时间截至2020年12月13日。

结果

结果显示,死亡病例频率最高的是≥60岁年龄组(n = 1897例患者;43.52%)和男性组(n = 2497例患者;57.28%)。病死率随年龄增长而上升,最高病死率出现在老年人(17.95%)、男性(7.60%)、帕蒂县(17.45%),而企业家(14.64%)是报告中占比最高的职业。此外,年龄最大组(≥60岁)和男性更容易死亡,比值比分别为5.49(95%置信区间:5.15 - 5.86)和1.61(95%置信区间:1.51 - 1.71)。大多数死亡病例患有合并症(65.79%),报告中最常见的合并症是糖尿病(n = 1387,31.82%)和高血压(n = 817,18.74%)。同时,老年患者更易合并其他疾病,p < 0.001,比值比为1.664(95%置信区间:1.425 - 1.944)。

结论

本研究得出结论,老年患者和男性可能比年轻患者和女性更容易死亡。需要进一步研究以衡量人口统计学的其他特征、基础疾病与病死率之间的关系。