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一丝希望之光：重症新型冠状病毒肺炎后的组织病理学及功能恢复

A spark of hope: histopathological and functional recovery after critical COVID-19.

作者信息

Boehm Anna, Luger Anna K, Schmitz Katja, Cima Katharina, Patscheider Daniel Hölbling, Augustin Florian, Jakob Lisa Maria, Obermayer Astrid, Weiss Guenter, Stoiber Walter, Widmann Gerlig, Loeffler-Ragg Judith

机构信息

Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.

Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria.

出版信息

Infection. 2022 Feb;50(1):263-267. doi: 10.1007/s15010-021-01678-7. Epub 2021 Aug 25.

DOI:10.1007/s15010-021-01678-7
PMID:34435313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8386898/
Abstract

BACKGROUND

There are substantial concerns about fibrotic and vascular pulmonary sequelae after coronavirus disease 2019 (COVID-19) associated acute respiratory distress syndrome (ARDS).AQ1 Histopathology reports of lung biopsies from COVID-19 survivors are scarce.

CASE

We herein report results of functional and histopathological studies in a 70 year-old man undergoing a co-incidental tumor lobectomy six months after long-term mechanical ventilation for COVID-19 pneumonia.

CONCLUSION

Despite several unfavorable risk factors, this case presentation shows a completed pulmonary recovery process within a few months.

摘要

背景

2019年冠状病毒病（COVID-19）相关急性呼吸窘迫综合征（ARDS）后肺部纤维化和血管后遗症备受关注。关于COVID-19幸存者肺活检的组织病理学报告稀缺。

病例

我们在此报告一名70岁男性的功能和组织病理学研究结果，该患者因COVID-19肺炎长期机械通气6个月后接受了意外的肿瘤肺叶切除术。

结论

尽管存在多个不利风险因素，但该病例显示在数月内肺部实现了完全恢复过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6974/8803741/f28a23609335/15010_2021_1678_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6974/8803741/89d54367a903/15010_2021_1678_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6974/8803741/f28a23609335/15010_2021_1678_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6974/8803741/89d54367a903/15010_2021_1678_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6974/8803741/f28a23609335/15010_2021_1678_Fig2_HTML.jpg

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Thorax. 2021 Feb;76(2):201-204. doi: 10.1136/thoraxjnl-2020-216088. Epub 2020 Nov 11.
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Age Matters but it should not be Used to Discriminate Against the Elderly in Allocating Scarce Resources in the Context of COVID-19.
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J Pers Med. 2023 Feb 1;13(2):282. doi: 10.3390/jpm13020282.
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One-year evolution of DLCO changes and respiratory symptoms in patients with post COVID-19 respiratory syndrome.新冠后呼吸综合征患者 DLCO 变化和呼吸症状的一年演变。
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年龄很重要，但在新冠疫情背景下分配稀缺资源时，不应以此为由歧视老年人。
Asian Bioeth Rev. 2020 Jun 16;12(3):331-340. doi: 10.1007/s41649-020-00130-6. eCollection 2020 Sep.