Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University Medical Center, Seoul 05355, Korea.
Department of Data Science, Sejong University College of Software Convergence, Seoul 05006, Korea.
Nutrients. 2021 Aug 17;13(8):2825. doi: 10.3390/nu13082825.
Breastfeeding is recommended due to its beneficial effects on human health. However, the effect of breastfeeding on health differs, resulting in various childhood diseases.
Our purpose was to investigate the association between breastfeeding at least in the first 4 months and the subsequent development of 15 certainly defined childhood diseases until 10 years of age, the all-cause hospitalization rate and growth at 6-7 years of age.
Participants included propensity-score matched 188,052 children born between January 2008 and December 2009, who were followed up till 10 years of age. Data were taken from the National Investigation of birth Cohort in Korea study 2008 database. Risk ratios were obtained using a modified Poisson regression and weighted risk differences using binomial regression.
Compared to formula feeding, breastfeeding was associated with decreased risks of febrile convulsion, attention deficit hyperactivity disorder and autism spectrum disorder, pneumonia, acute bronchiolitis, hypertrophic pyloric stenosis, asthma, all-cause hospitalization, overweight/obesity and short stature. Exclusive breastfeeding at 4 to 6 months of age had similar results to exclusive breastfeeding over 6 months of age.
Breastfeeding in early infancy reduces the risk for various childhood diseases, all-cause hospitalization rate, obesity, and short stature during childhood.
母乳喂养对人类健康有益，因此被推荐。然而，母乳喂养对健康的影响因疾病而异，导致了各种儿童疾病的发生。
本研究旨在调查至少在出生后前 4 个月进行母乳喂养与随后在 10 岁前发生 15 种特定定义的儿童疾病、全因住院率以及 6-7 岁时生长之间的关系。
本研究纳入了 2008 年 1 月至 2009 年 12 月出生的、经倾向评分匹配的 188052 名儿童作为研究对象，随访至 10 岁。数据来自 2008 年韩国全国出生队列研究数据库。使用校正泊松回归获得风险比，使用二项回归获得加权风险差异。
与配方奶喂养相比，母乳喂养与热性惊厥、注意缺陷多动障碍和自闭症谱系障碍、肺炎、急性细支气管炎、肥厚性幽门狭窄、哮喘、全因住院、超重/肥胖和身材矮小的风险降低相关。4 至 6 月龄的纯母乳喂养与 6 月龄以上的纯母乳喂养具有相似的结果。
婴儿期早期进行母乳喂养可降低各种儿童疾病、全因住院率、肥胖和儿童期身材矮小的风险。
