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母乳喂养与儿童住院的关系:韩国全国性出生队列研究。

Breastfeeding and impact on childhood hospital admissions: a nationwide birth cohort in South Korea.

机构信息

Department of Pediatrics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Republic of Korea.

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Nat Commun. 2023 Sep 20;14(1):5819. doi: 10.1038/s41467-023-41516-y.

DOI:10.1038/s41467-023-41516-y
PMID:37730734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10511528/
Abstract

Benefits of breastfeeding for both the mother and the child are well established, but a comprehensive and robust study to investigate the protective effect of breastfeeding and attenuated time effect stratified by cause of morbidity are lacking. This study is based on the nationwide birth cohort in Korea that includes data on all infants born from 2009 to 2015. Of 1,608,540 children, the median follow-up period was 8.41 years (interquartile range, 6.76-10.06). When compared to children with fully formula feeding, the hospital admission rate was 12% lower in those with partially breastfeeding and 15% lower in those with exclusive breastfeeding. The apparent protective effect of breastfeeding was reduced with increasing age. Our study provides potential evidence of the beneficial association of breastfeeding on subsequent hospital admissions. The protective effect declined over time as the children grew older. Encouraging any breastfeeding for at least the first 6 months among infants is an important public health strategy to improve overall child health.

摘要

母乳喂养对母亲和孩子都有好处,这已得到充分证实,但缺乏全面而有力的研究来调查母乳喂养的保护作用,并按发病原因分层分析减弱的时间效应。本研究基于韩国全国性的出生队列,其中包含了 2009 年至 2015 年所有婴儿的数据。在 1608540 名儿童中,中位随访期为 8.41 年(四分位间距,6.76-10.06)。与完全配方奶喂养的儿童相比,部分母乳喂养的儿童住院率低 12%,纯母乳喂养的儿童住院率低 15%。母乳喂养的明显保护作用随着年龄的增长而降低。我们的研究为母乳喂养对随后的住院治疗有有益关联提供了潜在证据。随着儿童年龄的增长,保护作用逐渐减弱。鼓励婴儿至少在前 6 个月进行任何形式的母乳喂养,是改善儿童整体健康的一项重要公共卫生策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/c95c051ef252/41467_2023_41516_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/6ba6b8535e1a/41467_2023_41516_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/6cdd7a7376f9/41467_2023_41516_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/c95c051ef252/41467_2023_41516_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/6ba6b8535e1a/41467_2023_41516_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/6cdd7a7376f9/41467_2023_41516_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf4/10511528/c95c051ef252/41467_2023_41516_Fig3_HTML.jpg

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