Butera Andrea, Pascadopoli Maurizio, Gallo Simone, Lelli Marco, Tarterini Fabrizio, Giglia Federico, Scribante Andrea
Unit of Dental Hygiene, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Polymers (Basel). 2021 Aug 16;13(16):2740. doi: 10.3390/polym13162740.
Toothpastes containing biomimetic hydroxyapatite have been investigated in recent years; the behavior of this material in the oral environment has been evaluated directly on dental enamel showing a marked remineralizing activity. To propose microRepair-based toothpastes (Zn-carbonate hydroxyapatite) for the domiciliary oral hygiene in patients with dental composite restorations, the aim of this study was to evaluate the deposition of Zn-carbonate hydroxyapatite on a polymeric composite resin with Scanning Electron Microscopy/Energy-Dispersive X-ray Spectrometry (SEM/EDS) analysis. Twenty healthy volunteers underwent the bonding of 3 orthodontic buttons on the vestibular surfaces of upper right premolars and first molar. On the surface of the buttons, a ball-shaped mass of composite resin was applied and light-cured. Then, the volunteers were randomly divided into two groups according to the toothpaste used for domiciliary oral hygiene: the Control toothpaste containing stannous fluoride and the Trial toothpaste containing microRepair. The buttons were debonded after 7 days (T1-first premolar), after 15 days (T2-second premolar), and after 30 days (T3-first molar) to undergo the SEM/EDS analysis. The deposition of calcium, phosphorus, and silicon was assessed through EDS analysis and data were submitted to statistical analysis ( < 0.05). SEM morphologic evaluation showed a marked deposition of the two toothpastes on the surfaces of the buttons. EDS quantitative analysis showed an increase of calcium, phosphorus, and silicon in both the groups, with a statistically significant difference of calcium deposition at T3 for the Trial group. Therefore, the use of toothpaste containing Zn-carbonate hydroxyapatite could be proposed as a device for domiciliary oral hygiene because the deposition of hydroxyapatite on polymeric composite resin could prevent secondary caries on the margins of restorations.
近年来，人们对含有仿生羟基磷灰石的牙膏进行了研究；该材料在口腔环境中的行为已直接在牙釉质上进行评估，显示出显著的再矿化活性。为了为牙科复合修复患者的家庭口腔卫生提出基于微修复的牙膏（碳酸锌羟基磷灰石），本研究的目的是通过扫描电子显微镜/能量色散X射线光谱分析（SEM/EDS）评估碳酸锌羟基磷灰石在聚合物复合树脂上的沉积情况。20名健康志愿者在上颌右前磨牙和第一磨牙的前庭表面粘结了3个正畸纽扣。在纽扣表面，涂抹一团球形复合树脂并进行光固化。然后，志愿者根据用于家庭口腔卫生的牙膏随机分为两组：含氟化亚锡的对照牙膏和含微修复的试验牙膏。在7天（T1 - 第一前磨牙）、15天（T2 - 第二前磨牙）和30天（T3 - 第一磨牙）后取下纽扣进行SEM/EDS分析。通过EDS分析评估钙、磷和硅的沉积情况，并将数据进行统计分析（<0.05）。SEM形态学评估显示两种牙膏在纽扣表面均有明显沉积。EDS定量分析显示两组中钙、磷和硅均增加，试验组在T3时钙沉积有统计学显著差异。因此，含碳酸锌羟基磷灰石的牙膏可作为家庭口腔卫生用品，因为羟基磷灰石在聚合物复合树脂上的沉积可预防修复边缘的继发龋。
