Salomoni Maria Giulia, Di Valerio Zeno, Gabrielli Elisa, Montalti Marco, Tedesco Dario, Guaraldi Federica, Gori Davide
Unit of Hygiene, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, 40126 Bologna, Italy.
Regional Authority for Healthcare and Welfare, Emilia-Romagna Region, 40126 Bologna, Italy.
Vaccines (Basel). 2021 Aug 6;9(8):873. doi: 10.3390/vaccines9080873.
Vaccination currently appears to be the only strategy to contain the spread of COVID-19. At the same time, vaccine hesitancy (VH) could limit its efficacy and has, therefore, attracted the attention of Public Health Systems. This systematic review aimed at assessing anti-COVID-19 vaccine acceptance rates worldwide and at identifying populations more prone to vaccine hesitancy, for which specific interventions should be planned. PubMed database was searched using a purposely formulated string. One hundred out of the 9243 studies retrieved were considered pertinent and thus included in the analyses. VH rate was analyzed according to patient geographical origin, ethnicity, age, study setting, and method used for data collection; data from specific populations were separately analyzed. Overall, this study demonstrated significant differences in terms of VH in the general population and in the specific subgroups examined according to geographical, demographic factors, as well as associated comorbidities, underlining the need for purposely designed studies in specific populations from the different countries, to design targeted programs aimed at increasing awareness for confidence and complacency toward COVID-19 vaccines.
目前，接种疫苗似乎是遏制新冠病毒传播的唯一策略。与此同时，疫苗犹豫可能会限制其效果，因此引起了公共卫生系统的关注。本系统综述旨在评估全球范围内抗新冠疫苗的接受率，并确定更容易出现疫苗犹豫的人群，以便制定针对性的干预措施。使用专门制定的检索词在PubMed数据库中进行检索。在检索到的9243项研究中，有100项被认为相关，因此纳入分析。根据患者的地理来源、种族、年龄、研究环境和数据收集方法分析疫苗犹豫率；对特定人群的数据进行单独分析。总体而言，本研究表明，根据地理、人口因素以及相关合并症，普通人群和特定亚组在疫苗犹豫方面存在显著差异，这突出表明需要针对不同国家的特定人群开展专门设计的研究，以制定有针对性的计划，提高人们对新冠疫苗的信心和接受度。
