Department of Anthropology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237, Łódź, Poland.
The Biobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
BMC Pediatr. 2021 Aug 27;21(1):365. doi: 10.1186/s12887-021-02837-3.
Cortisol is a steroid hormone acting as a stress hormone, which is crucial in regulating homeostasis. Previous studies have linked cortisol concentration to body mass and body composition.
The investigations were carried out in 2016-2017. A total of 176 children aged 6-13 years in primary schools in central Poland were investigated. Three types of measurements were performed: anthropometric (body weight and height, waist and hip circumferences), body composition (fat mass FM (%), muscle mass - MM (%), body cellular mass - BCM (%), total body water - TBW (%)), and cortisol concentration using saliva of the investigated individuals. Information about standard of living, type of feeding after birth, parental education and maternal trauma during pregnancy was obtained with questionnaires.
The results of regression models after removing the environmental factors (parental education, standard of living, type of feeding after birth, and maternal trauma during pregnancy) indicate a statistically significant association between the cortisol concentration and fat mass and muscle mass. The cortisol concentration was negatively associated with FM (%) (Beta=-0.171; p = 0.026), explaining 2.32 % of the fat mass variability and positively associated with MM (%) (Beta = 0.192; p = 0.012) explaining 3.09 % of the muscle mass variability.
Cortisol concentration affects fat and muscle mass among Polish children.
The Ethical Commission at the University of Lodz (nr 19/KBBN-UŁ/II/2016).
皮质醇是一种甾体激素，作为应激激素，在调节体内平衡方面起着至关重要的作用。先前的研究将皮质醇浓度与体重和身体成分联系起来。
该研究于 2016 年至 2017 年进行。共调查了波兰中部小学 176 名 6-13 岁的儿童。进行了三种类型的测量：人体测量学（体重和身高、腰围和臀围）、身体成分（脂肪量 FM（%）、肌肉量-MM（%）、身体细胞量-BCM（%）、总体液量-TBW（%）），以及使用唾液检测研究个体的皮质醇浓度。通过问卷调查获得有关生活水平、出生后喂养类型、父母教育程度和母亲怀孕期间创伤的信息。
在去除环境因素（父母教育程度、生活水平、出生后喂养类型和母亲怀孕期间创伤）后，回归模型的结果表明皮质醇浓度与脂肪量和肌肉量之间存在统计学上的显著关联。皮质醇浓度与 FM（%）呈负相关（Beta=-0.171；p=0.026），解释了脂肪量变异性的 2.32%，与 MM（%）呈正相关（Beta=0.192；p=0.012），解释了肌肉量变异性的 3.09%。
皮质醇浓度会影响波兰儿童的脂肪和肌肉量。
罗兹大学伦理委员会（nr 19/KBBN-UŁ/II/2016）。
