阻力运动干预对急性住院老年患者肌肉力量和功能的影响：7 项随机临床试验中 2498 例患者的系统评价和荟萃分析。
Resistance exercise intervention on muscular strength and power, and functional capacity in acute hospitalized older adults: a systematic review and meta-analysis of 2498 patients in 7 randomized clinical trials.
机构信息
Metabolism, Nutrition and Exercise Laboratory, Physical Education and Sport Center, Londrina State University, Rodovia Celso Garcia Cid, km 380, Londrina, Paraná, 86050-070, Brazil.
Applied Physiology, Nutrition and Exercise Research Group, Federal University of Triangulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.
出版信息
Geroscience. 2021 Dec;43(6):2693-2705. doi: 10.1007/s11357-021-00446-7. Epub 2021 Aug 28.
To date, no meta-analytical study evaluating the benefits of resistance exercise intervention on muscular strength and power and functional capacity in acute hospitalized older adults was conducted. Then, to synthesize the emerging evidence on the effects of resistance exercise intervention on muscular strength and power and functional capacity in acute hospitalized older adults, two independent authors performed a systematic search (PubMed, Scopus, Web of Science, and SciELO) until January 2021. Randomized clinical trials were included regarding the effects of resistance exercise and hospital usual care. The Cochrane Collaboration assessment tool was used to analyze the risk of bias. The comparisons included muscular strength (isometric handgrip strength and one-repetition maximum test of leg press), muscular power (output during leg press exercise), and functional capacity (timed-up-and-go, and short physical performance battery). Resistance exercise intervention increased muscular strength (isometric handgrip strength: mean difference = 2.50 kg, 95% confidence interval (CI) = 1.33, 3.67; and one-repetition maximum test of leg press: mean difference = 19.28 kg, 95% confidence interval = 14.70, 23.86) and muscular power (mean difference = 29.52 W, 95% confidence interval = 28.84, 30.21), and functional capacity (timed-up-and-go: mean difference = 3.40 s, 95% confidence interval = 0.47, 6.36; and short physical performance battery: mean difference = 1.29 points, 95% confidence interval = 0.10, 2.48) at discharge compared with hospital usual care. This meta-analysis endorses the increase of muscular strength and power gains and improving the functional capacity in favor of resistance exercise intervention in acute hospitalized older adults. TRIAL REGISTRATION : https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020203658.
迄今为止，尚无荟萃分析研究评估抗阻运动干预对急性住院老年患者肌肉力量和功能的益处。因此，为了综合评估抗阻运动干预对急性住院老年患者肌肉力量、功能的影响，两位独立作者进行了系统检索（PubMed、Scopus、Web of Science 和 SciELO），检索时间截至 2021 年 1 月。纳入了关于抗阻运动和医院常规护理的影响的随机临床试验。使用 Cochrane 协作风险偏倚评估工具进行分析。比较包括肌肉力量（握力、腿举 1 次重复最大力量测试）、肌肉力量（腿举运动时的输出）和功能能力（起立-行走测试、简短体能测试）。抗阻运动干预增加了肌肉力量（握力：平均差异=2.50 千克，95%置信区间=1.33 千克，3.67 千克；腿举 1 次重复最大力量测试：平均差异=19.28 千克，95%置信区间=14.70 千克，23.86 千克）和肌肉力量（平均差异=29.52 瓦特，95%置信区间=28.84 瓦特，30.21 瓦特）以及功能能力（起立-行走测试：平均差异=3.40 秒，95%置信区间=0.47 秒，6.36 秒；简短体能测试：平均差异=1.29 分，95%置信区间=0.10 分，2.48 分）与医院常规护理相比，出院时。这项荟萃分析支持增加肌肉力量和力量的增加，并改善功能能力有利于急性住院老年患者的抗阻运动干预。试验注册：https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020203658。
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