Mills George, Daynes Enya, McAuley Hamish J C, Greening Neil J, Briggs-Price Samuel, Baldwin Molly M, Singh Sally J
Centre of Exercise and Rehabilitation Science, NIHR Biomedical Research Centre - Respiratory, University Hospitals Leicester, Leicester, UK.
Department of Respiratory Sciences, University of Leicester, Leicester, UK.
J Frailty Sarcopenia Falls. 2023 Sep 1;8(3):188-194. doi: 10.22540/JFSF-08-188. eCollection 2023 Sep.
During hospitalisation with COVID-19, individuals may experience prolonged periods of immobilisation. Combined with the inflammatory effects of the virus, this may lead to a significant reduction in both muscle mass and strength. Data from several long-term studies suggest that these symptoms may not fully resolve within one year. Owing to its effectiveness at inducing muscle fibre hypertrophy and improving neuromuscular efficiency, resistance training is of great interest in the rehabilitation of this population. This narrative review aims to identify the rationale and potential efficacy of resistance training for restoring physical function following infection with SARS-CoV-2, as well as evidence of its use in clinical practice. The studies included in this narrative review consisted mostly of multi-component rehabilitation trials. Of these, widespread improvements in muscle strength were reported using intensities of up to 80% of participants' 1-repetition-maximum. Evidence thus far indicates that resistance training may be safe and effective in patients following COVID-19, although its individual contribution is difficult to discern. Future exercise intervention studies investigating the efficacy of resistance training as a sole modality are needed.
在因新冠肺炎住院期间，患者可能会经历长时间的活动受限。再加上病毒的炎症作用，这可能会导致肌肉质量和力量显著下降。多项长期研究的数据表明，这些症状可能在一年内无法完全缓解。由于抗阻训练在诱导肌纤维肥大和提高神经肌肉效率方面具有有效性，因此在该人群的康复中备受关注。本叙述性综述旨在确定抗阻训练对感染SARS-CoV-2后恢复身体功能的理论依据和潜在疗效，以及其在临床实践中的应用证据。本叙述性综述纳入的研究主要是多成分康复试验。其中，使用高达参与者1次最大重复量80%的强度时，肌肉力量有广泛改善的报告。迄今为止的证据表明，抗阻训练对新冠肺炎康复后的患者可能是安全有效的，尽管其个体贡献难以辨别。未来需要开展将抗阻训练作为单一方式的疗效的运动干预研究。
