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孕妇特定免疫状态与 SARS-CoV-2 感染的相互作用。

Interactions Between Specific Immune Status of Pregnant Women and SARS-CoV-2 Infection.

机构信息

Department of Anesthesiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

出版信息

Front Cell Infect Microbiol. 2021 Aug 12;11:721309. doi: 10.3389/fcimb.2021.721309. eCollection 2021.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the Coronavirus Disease 2019 (COVID-19) global pandemic. Because it is a new and highly contagious coronavirus, most people, especially pregnant women, lack immunity. It is therefore important to understand the interaction between why pregnant women are susceptible to SARS-CoV-2 and the specific immune systems of pregnant women. Here, we provide an overview of the changes that occur in the immune system during pregnancy, the activation and response of the immune system in pregnant women with COVID-19, adverse pregnancy outcomes in pregnant women with COVID-19, and the treatment and prevention of COVID-19 in this population.

摘要

严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是导致 2019 年冠状病毒病(COVID-19)全球大流行的病原体。由于它是一种新型且高度传染性的冠状病毒,大多数人,尤其是孕妇,缺乏免疫力。因此,了解孕妇易感染 SARS-CoV-2 的原因以及孕妇特定免疫系统之间的相互作用非常重要。在这里,我们概述了妊娠期间免疫系统发生的变化、COVID-19 孕妇免疫系统的激活和反应、COVID-19 孕妇的不良妊娠结局,以及该人群 COVID-19 的治疗和预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6913/8387674/3a87b5859695/fcimb-11-721309-g001.jpg

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