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肉毒杆菌毒素注射后面部潮红的一个不寻常征象:在肉毒杆菌毒素患者评估中纳入新问卷。

An unusual tell sign of botulinum toxin injection in patients with facial flushing: incorporating a new questionnaire in the evaluation of botulinum toxin patients.

机构信息

Department of Plastic Surgery, Saint Joseph University, Beirut, Lebanon.

Faculty of Medicine, Hotel Dieu de France Hospital, Beirut, Lebanon.

出版信息

J Cosmet Laser Ther. 2021 Feb 17;23(1-2):24-25. doi: 10.1080/14764172.2021.1957114. Epub 2021 Aug 30.

DOI:10.1080/14764172.2021.1957114
PMID:34459693
Abstract

Lately it has been established that intra-dermal botulinum toxin is also effective in treating many dermatological conditions including refractory erythematous-telangiectatic rosacea, post - menopausal facial flushing and other similar conditions.However, the desired effect of treating the reddening in patients suffering from facial flushing can become an undesirable and embarrassing side effect when these same patients present to the clinic for esthetic concerns such as upper face rhytids. In this case, intramuscular botulinum toxin injections used for wrinkles treatment will also secondarily treat the facial reddening in their localized skin diffusion zones and result in embarrassing white patches all over the face. The patchy appearance following botulinum toxin injections for esthetic purposes could be bothersome for some patients and could be a tell-tale sign of botulinum toxin injections.

摘要

最近已经证实,皮内注射肉毒毒素对于治疗多种皮肤科疾病也同样有效,包括难治性红斑毛细血管扩张性酒渣鼻、绝经后面部潮红和其他类似疾病。然而,当这些同样的患者因美容问题(如上面部皱纹)就诊时,治疗面部潮红患者的发红效果可能会成为一种不良且尴尬的副作用。在这种情况下,用于治疗皱纹的肌肉内肉毒毒素注射也会在局部皮肤扩散区域中继发治疗面部发红,并导致整个面部出现尴尬的白色斑块。出于美容目的而进行肉毒毒素注射后的这种片状外观可能会使一些患者感到困扰,并且可能是肉毒毒素注射的一个明显迹象。

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1
An unusual tell sign of botulinum toxin injection in patients with facial flushing: incorporating a new questionnaire in the evaluation of botulinum toxin patients.肉毒杆菌毒素注射后面部潮红的一个不寻常征象:在肉毒杆菌毒素患者评估中纳入新问卷。
J Cosmet Laser Ther. 2021 Feb 17;23(1-2):24-25. doi: 10.1080/14764172.2021.1957114. Epub 2021 Aug 30.
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Cosmetic indications for botulinum A toxin.A型肉毒杆菌毒素的美容适应症。
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Botulinum toxin injection for facial wrinkles.肉毒杆菌毒素注射治疗面部皱纹。
Am Fam Physician. 2014 Aug 1;90(3):168-75.
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Treatment of nasal wrinkles with botulinum toxin.肉毒杆菌毒素治疗鼻皱纹
Dermatol Surg. 2005 Mar;31(3):271-5. doi: 10.1111/j.1524-4725.2005.31072.
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Botulinum toxin for the treatment of refractory erythema and flushing of rosacea.肉毒杆菌毒素用于治疗玫瑰痤疮的难治性红斑和潮红。
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Botulinum Toxin A in Treatment of Facial Flushing.A型肉毒杆菌毒素治疗面部潮红
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Multipoint and multilevel injection technique of botulinum toxin A in facial aesthetics.A型肉毒毒素在面部美学中的多点多级注射技术
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Clinical indications and injection technique for the cosmetic use of botulinum A exotoxin.A型肉毒杆菌外毒素用于美容的临床适应症及注射技术。
Dermatol Surg. 1998 Nov;24(11):1189-94. doi: 10.1111/j.1524-4725.1998.tb04097.x.
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引用本文的文献

1
Botulinum Toxin A Alleviates Persistent Erythema and Flushing in Patients with Erythema Telangiectasia Rosacea.A型肉毒杆菌毒素可缓解红斑毛细血管扩张型玫瑰痤疮患者的持续性红斑和潮红。
Dermatol Ther (Heidelb). 2022 Oct;12(10):2285-2294. doi: 10.1007/s13555-022-00784-0. Epub 2022 Aug 4.