Laboratoire de Recherche sur les Produits Sanguins, Transfusion Interrégionale CRS, Épalinges, Switzerland; Faculté de Biologie et de Médecine, université de Lausanne, Lausanne, Switzerland.
Faculté de Biologie et de Médecine, université de Lausanne, Lausanne, Switzerland.
Transfus Clin Biol. 2021 Nov;28(4):397-402. doi: 10.1016/j.tracli.2021.08.344. Epub 2021 Aug 28.
The storage of red blood cells for transfusion purposes induces modifications of biochemical and biological properties. Moreover, these modifications are modulated by the donors' characteristics and the cell processing. These ex vivo alterations were suspected to decrease the transfusion efficiency and even to induce adverse events. This short article will review the red blood cells storage lesions and the clinical data related to them. In particular, the questions regarding the donors and recipients sex will be discussed.
为了输血目的而储存的红细胞会引起生化和生物学特性的改变。此外，这些改变还受到供体特征和细胞处理的调节。这些体外改变被怀疑会降低输血效率，甚至会引起不良反应。本文将综述红细胞储存损伤以及与之相关的临床数据。特别是，将讨论与供体和受者性别相关的问题。
