Wang Haiteng, Yu Ke, Yang Tianyi, Zeng Lingjing, Li Jialu, Dai Cimin, Peng Ziyi, Shao Yongcong, Fu Weiwei, Qi Jianlin
School of Psychology, Beijing Sport University, Beijing, China.
Department of Neurology, The General Hospital of Western Theater Command, Chengdu, China.
Front Neurosci. 2021 Aug 17;15:665687. doi: 10.3389/fnins.2021.665687. eCollection 2021.
Sleep loss not only compromises individual physiological functions but also induces a psychocognitive decline and even impairs the motor control and regulatory network. In this study, we analyzed whole-brain functional connectivity changes in the putamen and caudate nucleus as seed points in the neostriatum after 36 h of complete sleep deprivation in 30 healthy adult men by resting state functional magnetic resonance imaging to investigate the physiological mechanisms involved in impaired motor control and regulatory network in individuals in the sleep-deprived state. The functional connectivity between the putamen and the bilateral precentral, postcentral, superior temporal, and middle temporal gyrus, and the left caudate nucleus and the postcentral and inferior temporal gyrus were significantly reduced after 36 h of total sleep deprivation. This may contribute to impaired motor perception, fine motor control, and speech motor control in individuals. It may also provide some evidence for neurophysiological changes in the brain in the sleep-deprived state and shed new light on the study of the neostriatum in the basal ganglia.
睡眠不足不仅会损害个体的生理功能，还会导致心理认知能力下降，甚至损害运动控制和调节网络。在本研究中，我们通过静息态功能磁共振成像分析了30名健康成年男性在完全睡眠剥夺36小时后，以新纹状体中的壳核和尾状核为种子点的全脑功能连接变化，以研究睡眠剥夺状态下个体运动控制和调节网络受损的生理机制。完全睡眠剥夺36小时后，壳核与双侧中央前回、中央后回、颞上回和颞中回之间的功能连接，以及左侧尾状核与中央后回和颞下回之间的功能连接显著降低。这可能导致个体的运动感知、精细运动控制和言语运动控制受损。它还可能为睡眠剥夺状态下大脑的神经生理变化提供一些证据，并为基底神经节中纹状体的研究提供新的线索。
