Key Laboratory for Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, P. R. China.
Chongqing Key Laboratory of Bio-perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing, 400044, P. R. China.
Chem Commun (Camb). 2021 Sep 28;57(77):9870-9873. doi: 10.1039/d1cc03957a.
Herein, we develop a novel 3D composite aerogel (3D PB/GMA) and apply it to the real-time monitoring of HO secretion from living cells. The 3D PB/GMA shows an obvious porous structure and superior peroxidase-like activity. The electrochemical sensor based on 3D PB/GMA shows an excellent electrocatalytic performance towards HO. When applied to the real-time tracking of HO secretion from living cells, it can satisfactorily distinguish cancer cell lines from normal cell lines, revealing a good application potential in pathological diagnosis.
在这里，我们开发了一种新型的 3D 复合气凝胶（3D PB/GMA），并将其应用于活细胞中 HO 分泌的实时监测。3D PB/GMA 具有明显的多孔结构和优异的过氧化物酶样活性。基于 3D PB/GMA 的电化学传感器对 HO 表现出优异的电催化性能。当应用于实时跟踪活细胞中 HO 的分泌时，它可以令人满意地区分癌细胞系和正常细胞系，显示出在病理诊断中的良好应用潜力。
