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Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19.

作者信息

Yuan Lunzhi, Zhu Huachen, Zhou Ming, Ma Jian, Chen Rirong, Yu Liuqin, Chen Wenjia, Hong Wenshan, Wang Jia, Chen Yao, Wu Kun, Hou Wangheng, Zhang Yali, Ge Shengxiang, Chen Yixin, Yuan Quan, Tang Qiyi, Cheng Tong, Guan Yi, Xia Ningshao

机构信息

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, 361000, China.

State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China.

出版信息

Protein Cell. 2022 Jan;13(1):72-77. doi: 10.1007/s13238-021-00874-3. Epub 2021 Sep 7.

DOI:10.1007/s13238-021-00874-3
PMID:34491552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8422370/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9701/8776939/da7b5fdf0c74/13238_2021_874_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9701/8776939/0c3ad04bcf90/13238_2021_874_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9701/8776939/da7b5fdf0c74/13238_2021_874_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9701/8776939/0c3ad04bcf90/13238_2021_874_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9701/8776939/da7b5fdf0c74/13238_2021_874_Fig2_HTML.jpg

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本文引用的文献

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Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325.
Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control.
新发和再发传染病:全球趋势及预防和控制新策略。
Signal Transduct Target Ther. 2024 Sep 11;9(1):223. doi: 10.1038/s41392-024-01917-x.
4
Decisive reversal of lethal coronavirus disease 2019 in senescent hamster by synchronic antiviral and immunoregulatory intervention.通过同步抗病毒和免疫调节干预决定性逆转衰老仓鼠的致死性2019冠状病毒病
MedComm (2020). 2024 Jul 19;5(8):e642. doi: 10.1002/mco2.642. eCollection 2024 Aug.
5
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters.评估那法莫司他对仓鼠感染 SARS-CoV-2 的化学预防作用。
Viruses. 2023 Aug 15;15(8):1744. doi: 10.3390/v15081744.
6
Antiviral Nanobiologic Therapy Remodulates Innate Immune Responses to Highly Pathogenic Coronavirus.抗病毒纳米生物技术疗法重塑对高致病性冠状病毒的先天免疫反应。
Adv Sci (Weinh). 2023 Jun;10(17):e2207249. doi: 10.1002/advs.202207249. Epub 2023 Apr 25.
7
A Heterologous Challenge Rescues the Attenuated Immunogenicity of SARS-CoV-2 Omicron BA.1 Variant in Syrian Hamster Model.一种异源挑战可挽救 SARS-CoV-2 奥密克戎 BA.1 变异株在叙利亚仓鼠模型中的减毒免疫原性。
J Virol. 2023 Feb 28;97(2):e0168422. doi: 10.1128/jvi.01684-22. Epub 2023 Jan 18.
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Nasal irrigation efficiently attenuates SARS-CoV-2 Omicron infection, transmission and lung injury in the Syrian hamster model.鼻腔冲洗可有效减轻叙利亚仓鼠模型中SARS-CoV-2奥密克戎毒株的感染、传播和肺部损伤。
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Infection, pathology and interferon treatment of the SARS-CoV-2 Omicron BA.1 variant in juvenile, adult and aged Syrian hamsters.感染、病理学和干扰素对 SARS-CoV-2 奥密克戎 BA.1 变异株在幼年、成年和老年叙利亚仓鼠中的作用。
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