Department of Nutrition and Human Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68510, USA.
Department of Health, Kinesiology and Sport, University of South Alabama, Mobile, AL, 36688, USA.
J Int Soc Sports Nutr. 2021 Sep 9;18(1):60. doi: 10.1186/s12970-021-00456-y.
Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance. Furthermore, while polyphenols have antioxidant and anti-inflammatory properties, little is known regarding the influence of polyphenol supplementation on muscular strength, power, and endurance. Thus, the purpose of the present study was to compare the effects of 28 days of supplementation with phosphocreatine disodium salts plus blueberry extract (PCDSB), creatine monohydrate (CM), and placebo on measures of muscular strength, power, and endurance.
Thirty-three men were randomly assigned to consume either PCDSB, CM, or placebo for 28 days. Peak torque (PT), average power (AP), and percent decline for peak torque (PT%) and average power (AP%) were assessed from a fatigue test consisting of 50 maximal, unilateral, isokinetic leg extensions at 180°·s before and after the 28 days of supplementation. Individual responses were assessed to examine the proportion of subjects that exceeded a minimal important difference (MID).
The results demonstrated significant (p < 0.05) improvements in PT for the PCDSB and CM groups from pre- (99.90 ± 22.47 N·m and 99.95 ± 22.50 N·m, respectively) to post-supplementation (119.22 ± 29.87 N·m and 111.97 ± 24.50 N·m, respectively), but no significant (p = 0.112) change for the placebo group. The PCDSB and CM groups also exhibited significant improvements in AP from pre- (140.18 ± 32.08 W and 143.42 ± 33.84 W, respectively) to post-supplementation (170.12 ± 42.68 W and 159.78 ± 31.20 W, respectively), but no significant (p = 0.279) change for the placebo group. A significantly (p < 0.05) greater proportion of subjects in the PCDSB group exceeded the MID for PT compared to the placebo group, but there were no significant (p > 0.05) differences in the proportion of subjects exceeding the MID between the CM and placebo groups or between the CM and PCDSB groups.
These findings indicated that for the group mean responses, 28 days of supplementation with both PCDSB and CM resulted in increases in PT and AP. The PCDSB, however, may have an advantage over CM when compared to the placebo group for the proportion of individuals that respond favorably to supplementation with meaningful increases in muscular strength.
许多研究已经证明了肌酸补充剂在提高运动表现方面的功效。然而，很少有研究检查磷酸肌酸补充剂对运动表现的影响。此外，虽然多酚具有抗氧化和抗炎特性，但关于多酚补充剂对肌肉力量、功率和耐力的影响知之甚少。因此，本研究的目的是比较 28 天补充磷酸肌酸钠二钠盐和蓝莓提取物（PCDSB）、肌酸一水合物（CM）和安慰剂对肌肉力量、功率和耐力的影响。
33 名男性随机分为 PCDSB、CM 或安慰剂组，分别补充 28 天。在补充 28 天后，使用包括 50 次最大、单侧、180°·s 等速腿部伸展的疲劳测试，评估峰值扭矩（PT）、平均功率（AP）以及峰值扭矩（PT%）和平均功率（AP%）的下降幅度。评估个体反应，以检查超过最小有意义差异（MID）的受试者比例。
结果表明，PCDSB 和 CM 组的 PT 显著提高（p<0.05），分别从补充前（99.90±22.47 N·m 和 99.95±22.50 N·m）到补充后（119.22±29.87 N·m 和 111.97±24.50 N·m），而安慰剂组无显著变化（p=0.112）。PCDSB 和 CM 组的 AP 也有显著提高（分别从补充前的 140.18±32.08 W 和 143.42±33.84 W 到补充后的 170.12±42.68 W 和 159.78±31.20 W），而安慰剂组无显著变化（p=0.279）。与安慰剂组相比，PCDSB 组有更多的受试者超过了 PT 的 MID，而 CM 组与安慰剂组、CM 组与 PCDSB 组之间，受试者超过 MID 的比例没有显著差异（p>0.05）。
这些发现表明，对于组平均反应，28 天补充 PCDSB 和 CM 均可增加 PT 和 AP。然而，与 CM 相比，PCDSB 可能在安慰剂组中对肌肉力量有更有利的反应，具有更有意义的增加。
