Department of Pathology, Manipal College of Medical Science, Pokhara, Nepal.
Department of Radiology, Charak Memorial Hospital , Pokhara, Nepal.
JNMA J Nepal Med Assoc. 2020 Oct 15;58(230):729-735. doi: 10.31729/jnma.4898.
Salivary gland tumors are rare, comprising about 3% of all head and neck neoplasms. About 80% of the tumors are in parotids, 10% in submandibular glands and the remainders are distributed in sublingual and minor salivary glands. This study was conducted to evaluate the relative frequencies, types, site of distribution and the histopathological features of salivary gland tumors.
A descriptive cross-sectional study was conducted in the Department of Pathology, Manipal College of Medical Sciences, Pokhara from January 2011 to December 2019. Ethical approval was taken from the institutional review committee of Manipal College of Medical Sciences (Ref: 314). Convenient sampling was done among specimen. Data were entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 21.
Among the 130 specimens, the patients' age ranged from 6 to 78 years with a mean age of 37.26 years for benign tumors and 48.45 years for malignant tumors. There was female predominance with a male to female ratio of 1:1.36. There were 98 cases of benign tumors, commonest being pleomorphic adenoma with 82 (83.67%) cases which was noticed more frequently in fourth decade of life. Among the 32 malignant tumors, mucoepidermoid carcinoma was the commonest tumor 20 (62.5%), followed by adenoid cystic carcinoma 7 (23.33%).
Benign salivary gland tumors were more common than malignant tumors and the most common site of location was the parotid for both the benign and malignant tumors. Female outnumbered the male population in benign tumors whereas males were slightly more than females in malignant tumors. This study corroborated well with other previously published studies.
唾液腺肿瘤较为罕见，占头颈部肿瘤的 3%左右。约 80%的肿瘤发生于腮腺，10%发生于下颌下腺，其余分布于舌下腺和小唾液腺。本研究旨在评估唾液腺肿瘤的相对频率、类型、分布部位和组织病理学特征。
这是一项在 2011 年 1 月至 2019 年 12 月期间于尼泊尔博克拉的马尼帕尔医学院病理学系进行的描述性横断面研究。该研究已获得马尼帕尔医学院机构审查委员会的伦理批准（注册号：314）。采用便利抽样法选取标本。数据录入 Microsoft Excel 并使用统计软件包（第 21 版）进行分析。
在 130 例标本中，患者年龄为 6 至 78 岁，平均年龄为良性肿瘤 37.26 岁，恶性肿瘤 48.45 岁。女性多于男性，男女比例为 1:1.36。良性肿瘤 98 例，最常见的是多形性腺瘤，共 82 例（83.67%），多发于 40 岁左右。32 例恶性肿瘤中，黏液表皮样癌最常见，共 20 例（62.5%），其次是腺样囊性癌，共 7 例（23.33%）。
良性唾液腺肿瘤比恶性肿瘤更为常见，无论是良性还是恶性肿瘤，最常见的发生部位均为腮腺。良性肿瘤中女性多于男性，而恶性肿瘤中男性略多于女性。本研究与其他已发表的研究结果相符。
