Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Graduate School of Medical Sciences (Research School of Behavioural and Cognitive Neurosciences), University of Groningen, Groningen, The Netherlands.
Invest Ophthalmol Vis Sci. 2021 Sep 2;62(12):9. doi: 10.1167/iovs.62.12.9.
In glaucoma, visual field defects in the left and right eye may be non-overlapping, resulting in an intact binocular visual field. In clinical management, these patients are often considered to have normal vision. However, visual performance also relies on binocular processing. The aim of this study was to evaluate binocular visual functions in glaucoma patients with intact binocular visual field, normal visual acuity, and stereoscopy.
We measured in 10 glaucoma patients and 12 age-similar controls: (1) monocular and binocular contrast sensitivity functions (CSF) using a modified quick CSF test to assess binocular contrast summation, (2) dominance during rivalry, and (3) contrast ratio at balance point with a binocular phase combination test. A mirror stereoscope was used to combine the left and right eye image (each 10° horizontally by 12° vertically) on a display.
Area under the monocular and binocular CSF was lower in glaucoma compared to healthy (P < 0.001), but the binocular contrast summation ratio did not differ (P = 0.30). For rivalry, the percentage of time of mixed percept was 9% versus 18% (P = 0.056), the absolute difference of the percentage of time of dominance between the two eyes 19% versus 10% (P = 0.075), and the rivalry rate 8.2 versus 12.1 switches per minute (P = 0.017) for glaucoma and healthy, respectively. Median contrast ratio at balance point was 0.66 in glaucoma and 1.03 in controls (P = 0.011).
Binocular visual information processing deficits can be found in glaucoma patients with intact binocular visual field, normal visual acuity, and stereoscopy.
在青光眼患者中，左眼和右眼的视野缺损可能不重叠，从而导致双眼视野完整。在临床管理中，这些患者通常被认为视力正常。然而，视觉表现还依赖于双眼处理。本研究旨在评估具有完整双眼视野、正常视力和立体视的青光眼患者的双眼视觉功能。
我们测量了 10 名青光眼患者和 12 名年龄匹配的对照者的以下参数：（1）使用改良快速 CSF 测试测量单眼和双眼对比敏感度函数（CSF），以评估双眼对比总和；（2）竞争时的优势眼；（3）使用双眼相位组合测试测量平衡时的对比率。使用镜子立体镜将左眼和右眼的图像（每只眼水平 10°，垂直 12°）在显示器上组合。
与健康对照组相比，青光眼患者的单眼和双眼 CSF 曲线下面积较低（P < 0.001），但双眼对比总和比无差异（P = 0.30）。对于竞争，混合感知时间的百分比分别为 9%和 18%（P = 0.056），双眼优势眼时间的绝对差异为 19%和 10%（P = 0.075），竞争率分别为 8.2 和 12.1 次/分钟（P = 0.017）。青光眼和对照组的平衡时对比度比中位数分别为 0.66 和 1.03（P = 0.011）。
在具有完整双眼视野、正常视力和立体视的青光眼患者中，可发现双眼视觉信息处理缺陷。
