Guy's and St Thomas' NHS Foundation Trust, London, UK
Guy's and St Thomas' NHS Foundation Trust, London, UK and professor of obstetric medicine, King's Health Partners, London, UK.
Clin Med (Lond). 2021 Sep;21(5):e446-e450. doi: 10.7861/clinmed.2021-0503.
Pregnant women with COVID-19 are less likely to be symptomatic than non-pregnant counterparts. Risk factors for severe disease include being overweight or obese, greater than 35 years old, and having pre-existing comorbidities. Those who develop severe disease have increased rates of admission to an intensive care unit, requiring invasive ventilation and pre-term birth.Pregnant and breastfeeding women with COVID-19 should be investigated as of outside pregnancy and should receive proven therapies (such as corticosteroids and tocilizumab) on a risk/benefit basis. Admitted women should receive multidisciplinary care with input from senior decision makers and early escalation where required. There are no safety concerns -surrounding the COVID-19 vaccination and fertility or pregnancy, and so it should be offered to women based on their age and clinical risk group, in line with non-pregnant women.
与非孕妇相比，感染 COVID-19 的孕妇症状较轻。重症的危险因素包括超重或肥胖、年龄大于 35 岁和患有合并症。那些发展为重症的患者有更高的入住重症监护病房的几率，需要有创通气和早产。应按照非妊娠情况对患有 COVID-19 的孕妇和哺乳期妇女进行检查，并根据风险/获益情况给予已证实的治疗方法（如皮质类固醇和托珠单抗）。入院的患者应接受多学科治疗，包括资深决策者的意见，并在需要时及早升级治疗。COVID-19 疫苗接种与生育力或妊娠之间没有安全性问题，因此应根据妇女的年龄和临床风险组，与非孕妇一样，为其提供疫苗接种。
