Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran.
Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran.
Trop Anim Health Prod. 2021 Sep 17;53(5):449. doi: 10.1007/s11250-021-02918-6.
Bovine viral diarrhea virus (BVDV) is an important pathogen correlated with reproductive, respiratory, and gastrointestinal disorders in cattle. Furthermore, it causes endemic infections and significant economic losses in cattle herds worldwide. This review was performed to determine the pooled seroprevalence of BVDV infection and related risk factors among cattle in Iran. Data were systematically gathered without time limitation until 1 December 2020 in the Islamic Republic of Iran from the following electronic databases: PubMed, Google Scholar, Science Direct, Scopus, Web of Science, Elmnet, Magiran, Irandoc, Scientific Information Database (SID), and Civilica. According to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) and inclusion criteria, 28 eligible studies were obtained from various Iran areas. In total, the pooled seroprevalence of BVDV infection, using random-effect model, was estimated 52% (95% CI, 40.1-63.9) in cattle. According to serological detection methods, pooled seroprevalence was as follows: based on ELISA 53.9% and SVN 25.1%. The highest pooled seroprevalence of BVDV infection was in the southeast provinces of Iran (78.4%) and lowest pooled seroprevalence was in Southwest provinces of the country (28.5%). The pooled seroprevalence of BVDV infection in cattle ≤ 2 years was significantly lower than cattle > 2 years (OR = 0.606; 95% CI, 0.397-0.925), whereas the pooled seroprevalence had no significant difference according to other factors such as gender, herd size, and herd types. In conclusion, the pooled seroprevalence of BVDV infection among cattle in Iran is relatively high. The seroprevalence was different among geographical regions of the country. These results are desirable for managing the control programs of this infection in Iran.
牛病毒性腹泻病毒（BVDV）是一种与牛的生殖、呼吸和胃肠道疾病相关的重要病原体。此外，它在世界范围内的牛群中引起地方性感染和重大经济损失。本综述旨在确定伊朗牛群中 BVDV 感染的总血清流行率和相关风险因素。没有时间限制，从 2020 年 12 月 1 日起，在伊朗伊斯兰共和国从以下电子数据库系统地收集数据：PubMed、Google Scholar、Science Direct、Scopus、Web of Science、Elmnet、Magiran、Irandoc、Scientific Information Database (SID) 和 Civilica。根据系统评价和荟萃分析的首选报告项目（PRISMA）和纳入标准，从伊朗不同地区获得了 28 项符合条件的研究。使用随机效应模型，牛群 BVDV 感染的总血清流行率估计为 52%（95%CI，40.1-63.9）。根据血清学检测方法，总血清流行率如下：基于 ELISA 为 53.9%，SVN 为 25.1%。BVDV 感染的最高总血清流行率发生在伊朗东南部省份（78.4%），最低总血清流行率发生在该国西南部省份（28.5%）。牛群 BVDV 感染的总血清流行率在≤2 岁的牛中明显低于>2 岁的牛（OR=0.606；95%CI，0.397-0.925），而根据性别、畜群规模和畜群类型等其他因素，总血清流行率没有显著差异。总之，伊朗牛群中 BVDV 感染的总血清流行率相对较高。该流行率在该国不同地区存在差异。这些结果有助于管理伊朗该感染的控制计划。
