Shen Xu, Song Shenghua, Chen Nian, Liao Junlin, Zeng Li
Department of Medical Cosmetology, Hengyang Medical School, The First Affiliated Hospital, University of South China, Hengyang, China.
J Cosmet Dermatol. 2021 Dec;20(12):3812-3817. doi: 10.1111/jocd.14438. Epub 2021 Sep 18.
Stem cell-derived exosomes are cell-free vesicles secreted by stem cells. Exosomes play a pivotal role in cell-to cell communication due to the functional proteins and genetic information which they carry. In addition, studies on cell migration, tumor invasion, tissue regeneration, myocardial repair after injury, and fracture healing have been widely reported.
The purpose of this review is to sum up the current state of research on multiple stem cell-derived exosomes in cosmetic dermatology and to discuss the current challenges and future directions.
We searched "skin" and "exosome" from PubMed to find the application of stem cell exosomes in cosmetic dermatology.
We found that stem cell-derived exosomes have an important place in skin cosmetology such as wound healing, skin aging, and scar formation.
Stem cell derived exosomes supply a potential tool to cosmetic dermatology. The performance of stem cell derived exosomes in regulating skin physiological and pathobiological functions suggests that stem cell derived exosomes have potential in cosmetic dermatology.
干细胞来源的外泌体是干细胞分泌的无细胞囊泡。外泌体由于携带功能蛋白和遗传信息，在细胞间通讯中起关键作用。此外，关于细胞迁移、肿瘤侵袭、组织再生、损伤后心肌修复和骨折愈合的研究已有广泛报道。
本综述的目的是总结多能干细胞来源的外泌体在美容皮肤科的研究现状，并探讨当前面临的挑战和未来发展方向。
我们在PubMed上搜索了“皮肤”和“外泌体”，以查找干细胞外泌体在美容皮肤科的应用。
我们发现干细胞来源的外泌体在皮肤美容领域，如伤口愈合、皮肤老化和瘢痕形成方面具有重要地位。
干细胞来源的外泌体为美容皮肤科提供了一种潜在工具。干细胞来源的外泌体在调节皮肤生理和病理生物学功能方面的表现表明，其在美容皮肤科具有潜力。
