Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.
Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.
PLoS One. 2023 Sep 7;18(9):e0290414. doi: 10.1371/journal.pone.0290414. eCollection 2023.
To identify demographic and clinical factors predictive of having a missed opportunity (MO) for HIV screening.
Retrospective cohort study.
Electronic medical records were queried for individuals newly diagnosed with HIV in different sites within a large urban academic medical center in New York City between 2018 and 2022. The primary outcome was having one or more MO for HIV screening within the institution, defined as any encounter at which screening was not performed in the 365 days preceding the HIV diagnosis.
Over one third of new diagnoses had at least one MO in the preceding year. Older individuals, cisgender women and those assigned female sex at birth, and heterosexual individuals were more likely to have at least one MO. An initial CD4 < 200 cells/ul was more likely among men who have sex with women specifically. Most MOs occurred in the emergency department and outpatient settings, with minimal HIV prevention discussions documented during each MO.
These findings suggest that populations perceived to be at lower risk for HIV are more likely to have MOs and possibly late diagnoses, and that universal HIV screening must be implemented into the workflows of emergency department and outpatient settings to facilitate early diagnosis and reduce the incidence of HIV.
确定预测 HIV 筛查错失机会(MO)的人口统计学和临床因素。
回顾性队列研究。
在纽约市一家大型城市学术医疗中心的不同地点,对 2018 年至 2022 年期间新诊断出 HIV 的个体的电子病历进行了查询。主要结局是在该机构内发生一次或多次 HIV 筛查 MO,定义为在 HIV 诊断前的 365 天内未进行筛查的任何就诊。
超过三分之一的新诊断在过去一年中至少有一次 MO。年龄较大的个体、跨性别女性和出生时被指定为女性的个体以及异性恋个体更有可能发生至少一次 MO。特别是与女性发生性行为的男性中,初始 CD4<200 个细胞/μl 的情况更为常见。大多数 MO 发生在急诊室和门诊环境中,每个 MO 期间记录的 HIV 预防讨论很少。
这些发现表明,被认为 HIV 风险较低的人群更有可能发生 MO 并可能导致晚期诊断,并且必须将普遍的 HIV 筛查纳入急诊室和门诊环境的工作流程中,以促进早期诊断并减少 HIV 的发生率。